Results 101 to 110 of about 32,587 (229)

eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism [PDF]

, 2011
The activity of eIF4A, a key player in translation initiation, is regulated by other translation factors through currently unknown mechanisms. Here, we provide the necessary framework to understand the mechanism of eIF4A?s regulation by eIF4G.
Hilbert, M.
core   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis [PDF]

, 2007
Background The Oncomine™ database is an online collection of microarrays from various sources, usually cancer-related, and contains many "multi-arrays" (collections of analyzed microarrays, in a single study).
Giguère Vincent, Wilson Brian J
core   +2 more sources

The multiple lives of DEAD-box RNA helicase DP103/DDX20/Gemin3

Biochemical Society Transactions, 2018
Gemin3, also known as DDX20 or DP103, is a DEAD-box RNA helicase which is involved in more than one cellular process. Though RNA unwinding has been determined in vitro, it is surprisingly not required for all of its activities in cellular metabolism. Gemin3 is an essential gene, present in Amoeba and Metazoa.
Curmi, Frank, Cauchi, Ruben J.
openaire   +3 more sources

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Multi‐Omics Analysis Reveals Coordinated Adaptations in Genes, Metabolism, and Gut Microbiota Underpinning Herbivory in Lordiphosa Flies

Integrative Zoology, EarlyView.
Multi‐omics analysis reveals that herbivorous adaptation in Lordiphosa flies arises from coordinated interactions across the genome, transcriptome, and gut microbiota: genomic expansions of detoxification (e.g., cytochrome P450s) and carbohydrate metabolism gene families, transcriptomic upregulation of energy pathways like lipid oxidation and ...
Run Guo, Jianjun Gao, Caixian Zhang, Zhiheng Chang, Yanbo Sun   +4 more
wiley   +1 more source

Two highly similar DEAD box proteins, OsRH2 and OsRH34, homologous to eukaryotic initiation factor 4AIII, play roles of the exon junction complex in regulating growth and development in rice [PDF]

, 2016
Accession numbers and proteins homologous to eIF4A.
Chun-Kai Huang, Chung-An Lu, Tian-Sheng Huang, Yi-Syuan Sie, Yu-Fu Chen   +4 more
core   +3 more sources

DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation

Cell Reports, 2020
Summary: Embryonic stem cells (ESCs) exhibit high levels of ribosomal RNA (rRNA) transcription and ribosome biogenesis. Here, we reveal an unexpected role for an essential DEAD-box helicase, DDX18, in antagonizing the polycomb repressive complex 2 (PRC2)
Hui Zhang, Zhongyang Wu, J. Yuyang Lu, Bo Huang, Hongwei Zhou, Wei Xie, Jianlong Wang, Xiaohua Shen   +7 more
doaj   +1 more source

The two eIF4A helicases in Trypanosoma brucei are functionally distinct [PDF]

, 2006
Protozoan parasites belonging to the family Trypanosomatidae are characterized by an unusual pathway for the production of mRNAs via polycistronic transcription and trans-splicing of a 5' capped mini-exon which is linked to the 3' cleavage and ...
Campbell, Carrington, Caruthers, Caruthers, CHAN, Conti, De Gaudenzi, Dhalia, Gingras, Hirumi, Holzmann, Imataka, Ishigaki, Ivens, Kressler, Lejeune, Lejeune, Li, Li, Liang, Linder, Mair, Marcotrigiano, Minshall, Nielsen, Oberer, Palacios, Pause, Perry, Pestova, Pestova, Preiss, Rocak, Roditi, SHIBUYA, Skeiky, Skeiky, Sonenberg, Story, Svitkin, TANGE, Tanner, von der Haar, Webb, Wickstead, Wirtz, Yang, Yoder-Hill   +47 more
core   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source