Results 181 to 190 of about 10,578 (207)
African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation. [PDF]
Fan J +10 more
europepmc +1 more source
DEAD-box helicase gcDDX56 disrupts IRF3 nuclear import complex and promotes nuclear IRF3 degradation for enhancing GCRV replication. [PDF]
Xiao LL +5 more
europepmc +1 more source
From unwinding to clamping — the DEAD box RNA helicase family
RNA helicases of the DEAD box family are present in all eukaryotic cells and in many bacteria and Archaea. These highly conserved enzymes are required for RNA metabolism from transcription to degradation and are therefore important players in gene expression.
Patrick Linder +2 more
exaly +7 more sources
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The DEAD-box protein family of RNA helicases
Gene, 2006RNA helicases of the DEAD-box protein family have been shown to participate in every aspect of RNA metabolism. They are present in most organisms where they work as RNA helicases or RNPases. The properties of these enzymes in vivo remains poorly described, however some were extensively characterized in vitro, and the solved crystal structures of a few ...
Olivier Cordin +2 more
exaly +5 more sources
DEAD-box helicases as integrators of RNA, nucleotide and protein binding [PDF]
DEAD-box helicases perform diverse cellular functions in virtually all steps of RNA metabolism from Bacteria to Humans. Although DEAD-box helicases share a highly conserved core domain, the enzymes catalyze a wide range of biochemical reactions. In addition to the well established RNA unwinding and corresponding ATPase activities, DEAD-box helicases ...
Andrea Putnam, Eckhard Jankowsky
exaly +3 more sources
DEAD-Box RNA helicases in animal gametogenesis
Molecular Biology, 2014This review analyzes and summarizes a current knowledge about a role of RNA helicases in the development and maintenance of gametogenesis of eukaryotic organisms. Here we focused on three representatives of RNA helicase family containing the characteristic motifs in the amino acid sequence (DEAD-box) and carrying substantial and conservative functions ...
Alexei A Kotov, Ludmila V Olenina
exaly +3 more sources
The Ded1/DDX3 subfamily of DEAD-box RNA helicases
Critical Reviews in Biochemistry and Molecular Biology, 2014In eukaryotic organisms, the orthologs of the DEAD-box RNA helicase Ded1p from yeast and DDX3 from human form a well-defined subfamily that is characterized by high sequence conservation in their helicase core and their N- and C- termini. Individual members of this Ded1/DDX3 subfamily perform multiple functions in RNA metabolism in both nucleus and ...
Eckhard Jankowsky
exaly +3 more sources
A DEAD-box RNA helicase in the Escherichia coli RNA degradosome
Nature, 1996The Escherichia coli RNA degradosome is a multi-enzyme complex that contains the exoribonuclease polynucleotide phosphorylase (PNPase) and the endoribonuclease RNase E. Both enzymes are important in RNA processing and messenger RNA degradation. Here we report that enolase and RhlB are two other major components of the degradosome.
B, Py +3 more
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