Results 21 to 30 of about 53,995 (223)

Shedding light on optical cochlear implant progress

open access: yesEMBO Molecular Medicine, 2020
Electrical cochlear implants (CI) currently lack the frequency and intensity resolution to allow detection of complex sounds in background noise. The use of microscale optoelectronics in conjunction with optogenetics provides a promising direction in CI ...
Siân R Kitcher, Catherine JC Weisz
doaj   +1 more source

SWift -- A SignWriting editor to bridge between deaf world and e-learning [PDF]

open access: yesProceedings of the International Conference on Advanced Learning Technologies (ICALT), IEEE - Institute of Electrical and Electronics Engineers, pp.526-530, 2012, 978-0-7695-4702-2, 2019
SWift (SignWriting improved fast transcriber) is an advanced editor for SignWriting (SW). At present, SW is a promising alternative to provide documents in an easy-to-grasp written form of (any) Sign Language, the gestural way of communication which is widely adopted by the deaf community.
arxiv   +1 more source

Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms

open access: yesOncoImmunology, 2018
Loss or mutation of TP53 has been linked to alterations in anti-tumor immunity as well as dysregulation of cell cycle and apoptosis. We explored immunologic effects and mechanisms following restoration of wild-type human TP53 cDNA in murine oral cancer ...
Ellen C. Moore   +8 more
doaj   +1 more source

Determining if T cell antigens are naturally processed and presented on HLA class I molecules

open access: yesBMC Immunology, 2022
Background Determining T cell responses to naturally processed and presented antigens is a critical immune correlate to determine efficacy of an investigational immunotherapeutic in clinical trials.
Jay Friedman   +5 more
doaj   +1 more source

A concrete example of inclusive design: deaf-oriented accessibility [PDF]

open access: yesThe Wiley Handbook of Human Computer Interaction, 2 (chapter 33), Wiley (Blackwell), pp.731-756, 2018, 978-1-118-97613-5, 2019
One of the continuing challenges of Human Computer Interaction research is the full inclusion of people with special needs into the digital world. In particular, this crucial category includes people that experiences some kind of limitation in exploiting traditional information communication channels.
arxiv   +1 more source

PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation

open access: yesOncoImmunology, 2018
Preclinical evidence suggests that high-dose hypofractionated ionizing radiation (IR) can enhance anti-tumor immunity and result in significant tumor control when combined with immune checkpoint blockade (ICB).
Megan Morisada   +9 more
doaj   +1 more source

Towards improving the e-learning experience for deaf students: e-LUX [PDF]

open access: yesLecture Notes in Computer Science, Springer, 2014, Universal access in human-computer interaction: universal access to information and knowledge, 8514 (2), pp.221-232, 2019
Deaf people are more heavily affected by the digital divide than many would expect. Moreover, most accessibility guidelines addressing their needs just deal with captioning and audio-content transcription. However, this approach to the problem does not consider that deaf people have big troubles with vocal languages, even in their written form.
arxiv   +1 more source

Multilingual Communication System with Deaf Individuals Utilizing Natural and Visual Languages [PDF]

open access: yesarXiv, 2022
According to the World Federation of the Deaf, more than two hundred sign languages exist. Therefore, it is challenging to understand deaf individuals, even proficient sign language users, resulting in a barrier between the deaf community and the rest of society.
arxiv  

Sign Language Recognition System using TensorFlow Object Detection API [PDF]

open access: yes, 2022
Communication is defined as the act of sharing or exchanging information, ideas or feelings. To establish communication between two people, both of them are required to have knowledge and understanding of a common language. But in the case of deaf and dumb people, the means of communication are different.
arxiv   +1 more source

Gamma oscillations and application of 40‐Hz audiovisual stimulation to improve brain function

open access: yesBrain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Audiovisual stimulation, such as auditory stimulation, light stimulation, and audiovisual combined stimulation, as a non‐invasive stimulation, which can induce gamma oscillation, has received increased attention in recent years, and it has been preliminarily applied in the clinical rehabilitation of brain dysfunctions, such as ...
Xixi Chen   +6 more
wiley   +1 more source

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