Results 21 to 30 of about 141,941 (296)

Does probe-tube verification of real-ear hearing aid amplification characteristics improve outcomes in adult hearing aid users? A protocol for a systematic review

BMJ Open, 2020
Introduction Using a probe-tube microphone to measure and adjust the real-ear performance of the hearing aid to match the prescription target is recommended and widely used in clinical practice.
Kevin J Munro, Ibrahim Almufarrij, Harvey Dillon   +2 more
doaj   +1 more source

Cerebral lateralisation of first and second languages in bilinguals assessed using functional transcranial Doppler ultrasound [version 2; peer review: 2 approved, 1 not approved]

Wellcome Open Research, 2021
Background: Lateralised language processing is a well-established finding in monolinguals. In bilinguals, studies using fMRI have typically found substantial regional overlap between the two languages, though results may be influenced by factors such as ...
Dorothy V. M. Bishop, Clara R. Grabitz, Sophie C. Harte, Kate E. Watkins, Miho Sasaki, Eva Gutierrez-Sigut, Mairéad MacSweeney, Zoe V. J. Woodhead, Heather Payne   +8 more
doaj   +1 more source

Children, Deaf, of Deaf Parents [PDF]

, 2016
Deaf children with Deaf parents usually grow up in the Deaf community, that is if their parents offer them a sign language and are active members of the community. These Deaf children are similar to other children of linguistic and cultural minorities in many ways. They are also different in that they cannot, or at least not with the same ease as other
Baker, A.E., van den Bogaerde, B.
openaire   +4 more sources

Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms

OncoImmunology, 2018
Loss or mutation of TP53 has been linked to alterations in anti-tumor immunity as well as dysregulation of cell cycle and apoptosis. We explored immunologic effects and mechanisms following restoration of wild-type human TP53 cDNA in murine oral cancer ...
Ellen C. Moore, Lillian Sun, Paul E. Clavijo, Jay Friedman, Joe B. Harford, Anthony D. Saleh, Carter Van Waes, Esther H. Chang, Clint T. Allen   +8 more
doaj   +1 more source

PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation

OncoImmunology, 2018
Preclinical evidence suggests that high-dose hypofractionated ionizing radiation (IR) can enhance anti-tumor immunity and result in significant tumor control when combined with immune checkpoint blockade (ICB).
Megan Morisada, Paul E. Clavijo, Ellen Moore, Lillian Sun, Michael Chamberlin, Carter Van Waes, James W. Hodge, James B. Mitchell, Jay Friedman, Clint T. Allen   +9 more
doaj   +1 more source

Determining if T cell antigens are naturally processed and presented on HLA class I molecules

BMC Immunology, 2022
Background Determining T cell responses to naturally processed and presented antigens is a critical immune correlate to determine efficacy of an investigational immunotherapeutic in clinical trials.
Jay Friedman, Sreenivasulu Gunti, Maxwell Lee, Ke Bai, Christian Hinrichs, Clint T. Allen   +5 more
doaj   +1 more source

Shedding light on optical cochlear implant progress

EMBO Molecular Medicine, 2020
Electrical cochlear implants (CI) currently lack the frequency and intensity resolution to allow detection of complex sounds in background noise. The use of microscale optoelectronics in conjunction with optogenetics provides a promising direction in CI ...
Siân R Kitcher, Catherine JC Weisz
doaj   +1 more source

THE EDUCATION OF THE DEAF: [PDF]

The Lancet, 1911
n ...
openaire   +2 more sources

INF2‐Related Charcot–Marie–Tooth Disease in a Japanese Cohort: Genetic and Clinical Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background INF2 mutations cause focal segmental glomerulosclerosis (FSGS) and Charcot–Marie–Tooth disease (CMT). Accurate genetic diagnosis is critical, as INF2‐related FSGS is typically resistant to immunotherapy yet rarely recurs after transplantation, and its associated neuropathy can mimic treatable immune‐mediated disorders such as ...
Chikashi Yano, Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Takahiro Hobara, Risa Nagatomo, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Chika Matsuoka, Toru Yamashita, Takashi Kimura, Ayako Miyazaki, Chinatsu Kinjo, Kenji Yokochi, Nanami Yamanaka, Nozomu Matsuda, Tomoki Suichi, Yoshiyuki Hanaoka, Haruka Kojima, Kenichi Todo, Hiroyuki Ishiura, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +27 more
wiley   +1 more source

Multifunctional redox modulator prevents blast-induced loss of cochlear and vestibular hair cells and auditory spiral ganglion neurons

Scientific Reports
Blast wave exposure, a leading cause of hearing loss and balance dysfunction among military personnel, arises primarily from direct mechanical damage to the mechanosensory hair cells and supporting structures or indirectly through excessive oxidative ...
Dalian Ding, Senthilvelan Manohar, Peter F. Kador, Richard Salvi   +3 more
doaj   +1 more source