Results 21 to 30 of about 247,945 (341)

Bone conductive implants in single sided deafness [PDF]

open access: yes, 2015
Conclusion: The Bone Conductive Implants (BCI) showed to partly restore some of the functions lost when the binaural hearing is missing, such as in the single-sided deafness (SSD) subjects.
ATTURO, FRANCESCA   +4 more
core   +1 more source

Deaf mute or Deaf

open access: yesAsian Journal of Medical and Biological Research, 2017
Hearing loss is a common disorder and can be conductive, sensorineural or mixed types. It can be congenital or acquired. In pediatric population more than 50% of deafness is genetic in origin. The patients may present as Deaf, mute or hard of hearing.
Zaw Lin, Swe, Win Tin, Nang Khin Mya
openaire   +3 more sources

Single-Cell RNA-Seq of Cisplatin-Treated Adult Stria Vascularis Identifies Cell Type-Specific Regulatory Networks and Novel Therapeutic Gene Targets

open access: yesFrontiers in Molecular Neuroscience, 2021
The endocochlear potential (EP) generated by the stria vascularis (SV) is necessary for hair cell mechanotransduction in the mammalian cochlea. We sought to create a model of EP dysfunction for the purposes of transcriptional analysis and treatment ...
Ian A. Taukulis   +8 more
doaj   +1 more source

Does probe-tube verification of real-ear hearing aid amplification characteristics improve outcomes in adult hearing aid users? A protocol for a systematic review

open access: yesBMJ Open, 2020
Introduction Using a probe-tube microphone to measure and adjust the real-ear performance of the hearing aid to match the prescription target is recommended and widely used in clinical practice.
Kevin J Munro   +2 more
doaj   +1 more source

Is the outcome of fitting hearing aids to adults affected by whether an audiogram-based prescription formula is individually applied? A systematic review protocol

open access: yesBMJ Open, 2021
Introduction Hearing aids are typically programmed using the individual’s audiometric thresholds. Developments in technology have resulted in a new category of direct-to-consumer devices, which are not programmed using the individual’s audiometric ...
Kevin J Munro   +2 more
doaj   +1 more source

Enhancing direct cytotoxicity and response to immune checkpoint blockade following ionizing radiation with Wee1 kinase inhibition

open access: yesOncoImmunology, 2019
Tumor cells activate the G2/M cell cycle checkpoint in response to ionizing radiation (IR) and effector immune cell-derived granzyme B to facilitate repair and survival. Wee1 kinase inhibition reverses the ability of tumor cells to pause at G2/M.
Priya Patel   +9 more
doaj   +1 more source

Refining surgical techniques for efficient posterior semicircular canal gene delivery in the adult mammalian inner ear with minimal hearing loss

open access: yesScientific Reports, 2021
Hearing loss is a common disability affecting the world’s population today. While several studies have shown that inner ear gene therapy can be successfully applied to mouse models of hereditary hearing loss to improve hearing, most of these studies rely
Jianliang Zhu   +6 more
doaj   +1 more source

Cerebral lateralisation of first and second languages in bilinguals assessed using functional transcranial Doppler ultrasound [version 2; peer review: 2 approved, 1 not approved]

open access: yesWellcome Open Research, 2021
Background: Lateralised language processing is a well-established finding in monolinguals. In bilinguals, studies using fMRI have typically found substantial regional overlap between the two languages, though results may be influenced by factors such as ...
Dorothy V. M. Bishop   +8 more
doaj   +1 more source

Children, Deaf, of Deaf Parents [PDF]

open access: yes, 2016
Deaf children with Deaf parents usually grow up in the Deaf community, that is if their parents offer them a sign language and are active members of the community. These Deaf children are similar to other children of linguistic and cultural minorities in many ways. They are also different in that they cannot, or at least not with the same ease as other
Baker, A.E., van den Bogaerde, B.
openaire   +4 more sources

Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms

open access: yesOncoImmunology, 2018
Loss or mutation of TP53 has been linked to alterations in anti-tumor immunity as well as dysregulation of cell cycle and apoptosis. We explored immunologic effects and mechanisms following restoration of wild-type human TP53 cDNA in murine oral cancer ...
Ellen C. Moore   +8 more
doaj   +1 more source

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