Results 41 to 50 of about 141,941 (296)

The impact of face coverings on audio-visual contributions to communication with conversational speech

Cognitive Research
The use of face coverings can make communication more difficult by removing access to visual cues as well as affecting the physical transmission of speech sounds.
I. R. Jackson, E. Perugia, M. A. Stone, G. H. Saunders   +3 more
doaj   +1 more source

Cisplatin is retained in the cochlea indefinitely following chemotherapy

Nature Communications, 2017
Permanent hearing loss occurs in many cancer patients treated with cisplatin. In this study, the authors examine cisplatin pharmacokinetics in the cochleae of mice and humans showing that cisplatin is retained for months to years after treatment.
Andrew M. Breglio, Aaron E. Rusheen, Eric D. Shide, Katharine A. Fernandez, Katie K. Spielbauer, Katherine M. McLachlin, Matthew D. Hall, Lauren Amable, Lisa L. Cunningham   +8 more
doaj   +1 more source

Synaptic mitochondria regulate hair-cell synapse size and function

eLife, 2019
Sensory hair cells in the ear utilize specialized ribbon synapses. These synapses are defined by electron-dense presynaptic structures called ribbons, composed primarily of the structural protein Ribeye.
Hiu-tung C Wong, Qiuxiang Zhang, Alisha J Beirl, Ronald S Petralia, Ya-Xian Wang, Katie Kindt   +5 more
doaj   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone, Alessia Nisco, Luciana de Gennaro, Maria Tolomeo, Elisa Lorefice, Giuseppe Petrosillo, Silvia Russo, Donatella De Giovanni, Claudia Rita Catacchio, Francesca Romana Lepri, Mario Ventura, Simonetta Simonetti, Albina Tummolo, Maria Barile   +13 more
wiley   +1 more source

Deafness gene screening based on a multilevel cascaded BPNN model

BMC Bioinformatics, 2023
Sudden sensorineural hearing loss is a common and frequently occurring condition in otolaryngology. Existing studies have shown that sudden sensorineural hearing loss is closely associated with mutations in genes for inherited deafness. To identify these
Xiao Liu, Li Teng, Wenqi Zuo, Shixun Zhong, Yuqiao Xu, Jing Sun   +5 more
doaj   +1 more source

Intergenerational Family Relationships and Old‐Age Volunteering: The Perspectives of Older Chinese Immigrants in Greater Sydney, Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT Embedded in the framework of intergenerational solidarity, this paper explores the interactions between older immigrants' participation in volunteering activities and intergenerational family relationships in the Chinese community in Sydney, Australia. The study investigates the effects of volunteering on the lives of older Chinese immigrants.
Bingqin Li, Yiran Li, Alan Morris, Youqing Fan, Xin Gu, Ilan Katz   +5 more
wiley   +1 more source

Meeting the Needs of Aboriginal and Torres Strait Islander People With Hearing Loss in the Context of the National Disability Insurance Scheme

Australian Journal of Social Issues, EarlyView.
ABSTRACT Hearing loss is a poignant issue in many Aboriginal and Torres Strait Islander communities and, without sufficient support, it can also contribute to disabling life experiences. The National Disability Insurance Scheme (NDIS) is intended to provide support to eligible people experiencing disability, however, to effectively serve this ...
Hannah Lack, Jody Barney, Marie Huska, Damien Howard, Alexandra Devine   +4 more
wiley   +1 more source

A novel G21R mutation of the GJB2 gene causes autosomal dominant non-syndromic congenital deafness in a Cuban family

Genetics and Molecular Biology, 2006
Deafness is a complex disorder affecting 1/1000 infants. In developed countries, more than 50% of deafness cases are thought to have a genetic cause. At least 40 loci for dominant non-syndromic deafness and another 30 for recessive non-syndromic deafness
Raquel Rabionet, Estela Morales-Peralta, Núria López-Bigas, Maria Lourdes Arbonés, Xavier Estivill   +4 more
doaj   +1 more source

Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

eLife, 2020
Directional sensitivity of hair cells (HCs) is conferred by the aymmetric apical hair bundle, comprised of a kinocilium and stereocilia staircase. The mother centriole (MC) forms the base of the kinocilium and the stereocilia develop adjacent to it ...
Yosuke Tona, Doris K Wu
doaj   +1 more source

Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Poor vascular health has been associated with age‐related declines in sensory functions, including olfaction. The current study was designed to test the hypothesis that cerebral small vessel disease underlies poor olfactory function due to structural declines in brain regions that support olfaction.
Mark A. Eckert, Judy R. Dubno, Zachary M. Soler, Rodney J. Schlosser   +3 more
wiley   +1 more source