Results 81 to 90 of about 365,870 (389)

Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

open access: yeseLife, 2020
Directional sensitivity of hair cells (HCs) is conferred by the aymmetric apical hair bundle, comprised of a kinocilium and stereocilia staircase. The mother centriole (MC) forms the base of the kinocilium and the stereocilia develop adjacent to it ...
Yosuke Tona, Doris K Wu
doaj   +1 more source

Correlations between appraisals, management strategies, and psychological stress among schoolchildren with ADHD—A pilot study

open access: yesJCPP Advances, EarlyView.
Abstract Background Children with Attention‐Deficit/Hyperactivity Disorder (ADHD) encounter a range of difficulties in daily life. Guided by previous studies and theories, this pilot study examined whether distinct subgroups of children with ADHD could be identified based on their appraisals of the causes of their symptoms and the strategies they use ...
Noam Ringer, Adva Eichengreen
wiley   +1 more source

Psychosocial Outcomes in Long-Term Cochlear Implant Users [PDF]

open access: yes, 2018
OBJECTIVES: The objectives of this study were to investigate psychosocial outcomes in a sample of prelingually deaf, early-implanted children, adolescents, and young adults who are long-term cochlear implant (CI) users and to examine the extent to ...
Castellanos, Irina   +2 more
core   +1 more source

A novel G21R mutation of the GJB2 gene causes autosomal dominant non-syndromic congenital deafness in a Cuban family

open access: yesGenetics and Molecular Biology, 2006
Deafness is a complex disorder affecting 1/1000 infants. In developed countries, more than 50% of deafness cases are thought to have a genetic cause. At least 40 loci for dominant non-syndromic deafness and another 30 for recessive non-syndromic deafness
Raquel Rabionet   +4 more
doaj   +1 more source

Rescue of hearing and vestibular function in a mouse model of human deafness

open access: yesNature Medicine, 2013
Hearing impairment is the most common sensory disorder, with congenital hearing impairment present in approximately 1 in 1,000 newborns. Hereditary deafness is often mediated by the improper development or degeneration of cochlear hair cells.
J. Lentz   +9 more
semanticscholar   +1 more source

A Novel Murine Model of Acute Laryngeal Injury After Intubation

open access: yesThe Laryngoscope, EarlyView.
This study describes a novel murine model of acute laryngeal injury (ALgI) after intubation. Chemomechanical injury was performed to the posterior glottis of adult mice using a bleomycin‐dipped wire brush under endoscopic guidance, resulting in reduced glottic mobility, increased posterior glottic thickness, and increased collagen expression. This safe,
Ruth J. Davis   +4 more
wiley   +1 more source

OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation. [PDF]

open access: yes, 2015
Hearing impairment is the second most prevalent clinical feature after optic atrophy in Dominant Optic Atrophy associated with mutations in the OPA1 gene.
Arslan, E   +12 more
core   +3 more sources

Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis

open access: yesFrontiers in Molecular Neuroscience, 2019
The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell mechanotransduction and hearing.
Soumya Korrapati   +10 more
doaj   +1 more source

Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods

open access: yesThe Laryngoscope, EarlyView.
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King   +2 more
wiley   +1 more source

Effects of neoadjuvant immunotherapy on hearing in patients with head and neck squamous cell carcinoma

open access: yesScientific Reports
Immune checkpoint blockade (ICB) is a commonly used treatment modality for cancer with a growing list of oncologic indications. Ototoxicity is a potential immune-related adverse event of ICB treatment, but the risk of hearing loss after ICB remains ...
Bryce Hambach   +11 more
doaj   +1 more source

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