Results 81 to 90 of about 53,995 (223)
Advanced Science, EarlyView.Drug‐induced renal damage impairs uric acid excretion, causing its accumulation in the serum, which subsequently infiltrates the cochlea. Xanthine oxidase and the ABCG2 transporter, critical in uric acid metabolism and excretion, undergo pathological changes in renal tubular and cochlear stria vascularis cells.
Suhan Guo +11 more
wiley +1 more source
Advanced Science, EarlyView.Micromagnetic stimulation (µMS) offers a precise method for neural inhibition, complementing existing neuromodulation techniques. Using an implantable micro‐coil device, µMS selectively suppresses cortical activity with high spatial resolution. It effectively counteracts micro‐electrode stimulation and reduces seizure amplitude, highlighting its ...
Kayeon Kim +11 more
wiley +1 more source
Advanced Science, EarlyView.Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian +5 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.Ultrathin ITO and ferroelectric HZO are used to fabricate synaptic transistors. The device has a great on/off ratio ≈108 with a memory window of 1.73 V, successfully simulates the characteristics of the human brain, and achieves good linearity of 0.45 for potential and 0.73 for depression and low asymmetry of 0.89.
Siwei Wang +8 more
wiley +1 more source
American Journal of Community Psychology, EarlyView.Abstract Immigrants and refugees in the United States often face significant barriers in accessing social services, including mental health support, legal assistance, ESL or related education, housing, vocational training, workforce resources, transportation, and citizenship support. This article explores the strengths and challenges of community‐based
Rooshey Hasnain +7 more
wiley +1 more source
Neural Plasticity, 2016 Nonsyndromic deafness is genetically heterogeneous but phenotypically similar among many cases. Though a variety of targeted next-generation sequencing (NGS) panels has been recently developed to facilitate genetic screening of nonsyndromic deafness ...
Penghui Chen +5 more
doaj +1 more source
Early deafness leads to re-shaping of global functional connectivity beyond the auditory cortex [PDF]
arXiv, 2019 Early sensory deprivation such as blindness or deafness shapes brain development in multiple ways. While it is established that deprived brain areas start to be engaged in the processing of stimuli from the remaining modalities and in high-level cognitive tasks, some reports have also suggested the possibility of structural and functional changes in ...
arxiv
A Pilot Study to Evaluate Neurodevelopmental Outcomes in a Pediatric Cohort With Genodermatoses
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Our study aimed to evaluate cognitive function in individuals with genetic skin disorders involving neuroectoderm (n = 8) compared to individuals with only ectoderm or mesoderm (n = 16) involvement. We hypothesized that neuroectodermal involvement would result in poorer neurocognitive performance.
Sneha A. Rangu +10 more
wiley +1 more source
MTSS2‐Related Disorder: Refining the Phenotype in Four New Cases and Literature Review
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT MTSS2 encodes a protein highly expressed in the central nervous system, with a crucial role in neurodevelopment. The de novo recurrent variant c.2011C>T (p.Arg671Trp) was first identified in 2022 as cause of Intellectual Developmental Disorder with ocular anomalies and distinctive facial features (OMIM#620086).
Angela De Dominicis +12 more
wiley +1 more source
Australian Journal of Social Issues, EarlyView.ABSTRACT Embedded in the framework of intergenerational solidarity, this paper explores the interactions between older immigrants' participation in volunteering activities and intergenerational family relationships in the Chinese community in Sydney, Australia. The study investigates the effects of volunteering on the lives of older Chinese immigrants.
Bingqin Li +5 more
wiley +1 more source