Results 151 to 160 of about 16,074 (213)

Improving 1-Deamino-8-D-Arginine Vasopressin (DDAVP) Challenges in Pediatric/Young Adult Patients With Bleeding Disorders: A Quality Improvement Study

Journal of Pediatric Hematology/Oncology Nursing
Background: Desmopressin (1-deamino-8-D-arginine vasopressin [DDAVP]) has demonstrated efficacy as a treatment option for patients with inherited bleeding disorders.
Michelle Hallam, Amber Pruett, Charmaine Biega, Haley Miller, Tami Davis, Linda Casto, Amy L. Dunn, Vilmarie Rodriguez   +7 more
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Research Progress of 1-Deamino-8-D-Arginine-Vasopressin in the Treatment of Patients With Hemophilia

, 2011
1-deamino-8-D-arginine-vasopressin (DDAVP) is a synthetic compound of the antidiuretic hormone vasopressin, which can increase plasma concentration of factor Ⅷ (FⅧ), von Willebrand factor (vWF), and tissue plasminogen activator (t-PA) in normal subjects ...
Songting Bai
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Molecular mechanics calculations on deaminooxytocin and on deamino-arginine-vasopressin and its analogues

J. Comput. Aided Mol. Des., 1989
Adam Liwo, Anna Tempczyk, Zbigniew Grzonka   +2 more
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Synthesis and some pharmacological properties of deamino(4-threonine,8-D-arginine)vasopressin and deamino(8-D-arginine)vasopressin, highly potent and specific antidiuretic peptides, and (8-D-arginine)vasopressin and deamino-arginine-vasopressin.

Journal of Medicinal Chemistry, 1976
Deamino[4-threonine,8-D-arginine]vasopressin (dTDAVP), deamino[8-D-arginine]vasopressin (dDAVP), [8-D-arginine[vasopressin (DAVP), and deamino-arginine-vasopressin (dAVP) were synthesized by the solid-phase method and tested for their biological ...
M. Manning, L. Balaspiri, J. Moehring, J. Haldar, W. Sawyer   +4 more
semanticscholar   +1 more source

2-O-alkyltyrosine derivatives of 1-deamino-arginine-vasopressin: highly specific and potent antidiuretic agonists.

Journal of Medicinal Chemistry, 1989
We report the solid-phase synthesis of eight 2-O-alkyltyrosine analogues of 1-deamino-arginine-vasopressin (dAVP) with enhanced antidiuretic agonistic specificity. These peptides are as follows: 1-deamino[2-O-methyltyrosine]-arginine-vasopressin (dTyr(Me)
B. Lammek, K. Bańkowski, A. Misicka, M. Manning, J. Seto, W. Sawyer   +5 more
semanticscholar   +1 more source

Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells.

Future Medicinal Chemistry, 2011
BACKGROUND Desmopressin (dDAVP), a synthetic nonapeptide derivative of arginine vasopressin, is a safe antidiuretic and hemostatic compound that acts as a selective agonist for the vasopressin V2 membrane receptor (V2R).
N. Iannucci, Giselle V. Ripoll, Juan Garona, O. Cascone, G. Ciccia, D. Gomez, D. Alonso   +6 more
semanticscholar   +1 more source

Amino acids and peptides. LXXI. Synthesis of 1-deamino-8-D-γ-aminobutyrine-vasopressin, 1-deamino-8-D-lysine-vasopressin, and 1-deamino-8-D-arginine-vasopressin

, 1967
M. Zaoral, J Kolc, F. Šorm
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Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia.

New England Journal of Medicine, 1983
In a randomized double-blind cross-over trial we gave either 1-deamino-8-D-arginine vasopressin or placebo to 12 patients with uremia, hemorrhagic tendencies, and prolonged bleeding times.
P. Mannucci, G. Remuzzi, F. Pusineri, R. Lombardi, C. Valsecchi, G. Mecca, T. Zimmerman   +6 more
semanticscholar   +1 more source

Intranasal deamino-8-D-arginine vasopressin shortens the bleeding time in uremia.

American Journal of Nephrology, 1984
Clinical bleeding in uremia is a frequent problem and seems to correlate with a prolonged bleeding time. The vasopressin analog deamino-8-D-arginine vasopressin has been shown to shorten the bleeding time and to decrease clinical bleeding when ...
M. Shapiro, S. Kelleher
semanticscholar   +1 more source

Plasma concentrations of 1-deamino-8-D-arginine vasopressin after intragastric administration in the rat.

Acta Endocrinologica, 1985
A sensitive and specific radioimmunoassay for 1-deamino-8-D-arginine vasopressin (DDAVP) was developed. Plasma concentrations of DDAVP after intragastric administration were determined in non-fasted rats and a dose-related increase in plasma levels was ...
S. Lundin, P. Melin, H. Vilhardt
semanticscholar   +1 more source