Results 161 to 170 of about 16,210 (237)

Solid-phase synthesis and some pharmacological properties of deamino-4-threonine analogs of the vasopressins and vasotocin and [deamino]arginine-vasotocin

Chemischer Informationsdienst, 1973
AbstractNach der Festphasenmethode werden die Vasopressine (I) und (III) sowie die Vasotocine (II) und (IV) dargestellt.
Maurice Manning, Esther J. Coy, M. ACOSTA, Wilbur H. Sawyer   +3 more
openalex   +5 more sources

Effects of lysine-vasopressin and 1-deamino-8-d-arginine-vasopressin on memory in healthy individuals and diabetes insipidus patients

Psychoneuroendocrinology, 1982
Central diabetes insipidus (DI) patients showed impairments in short- and long-term memory functions, but not in attention and concentration, as compared to healthy individuals. A single i.m. injection or sub-chronic intranasal administration of either lysine-vasopressin (LVP) or 1-deamino-8-D-arginine-vasopressin (DDAVP) normalized the disturbed ...
F. Laczi, Zs. Valkusz, Ferenc László, A Wagner, T. Járdánházy, Anna Szász, J. Szilárd, Gyula Telegdy   +7 more
openalex   +5 more sources

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Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells.

Future Medicinal Chemistry, 2011
BACKGROUND Desmopressin (dDAVP), a synthetic nonapeptide derivative of arginine vasopressin, is a safe antidiuretic and hemostatic compound that acts as a selective agonist for the vasopressin V2 membrane receptor (V2R).
N. Iannucci, Giselle V. Ripoll, Juan Garona, O. Cascone, G. Ciccia, D. Gomez, D. Alonso   +6 more
semanticscholar   +4 more sources

Effect of 1-deamino-8-D-arginine vasopressin on the prolonged bleeding time in chronic renal failure.

Nephron, 1982
The prolonged bleeding times of 12 patients with chronic renal failure were significantly shortened at 1 and 2 h after an infusion of 0.4 microgram/kg 1-deamino-8-D-arginine vasopressin (DDAVP).
A. Watson, J. Keogh
semanticscholar   +4 more sources

SHORTENING OF BLEEDING TIME BY 1-DEAMINO-8-D-ARGININE VASOPRESSIN IN VARIOUS BLEEDING DISORDERS

The Lancet, 1984
To evaluate the effect of 1-deamino-8-D-arginine vasopressin (DDAVP) in various bleeding disorders, 10 micrograms/m2 DDAVP was administered to subjects with von Willebrand disease (13), platelet function defects (12), von Willebrand disease and platelet defects together (8), or isolated prolongation of the bleeding time (5).
N. Kobrinsky, J. Gerrard, C. Watson, E. Israels, M. Cheang, A. Bishop, M. Schroeder   +6 more
semanticscholar   +4 more sources

Research Progress of 1-Deamino-8-D-Arginine-Vasopressin in the Treatment of Patients With Hemophilia

, 2011
1-deamino-8-D-arginine-vasopressin (DDAVP) is a synthetic compound of the antidiuretic hormone vasopressin, which can increase plasma concentration of factor Ⅷ (FⅧ), von Willebrand factor (vWF), and tissue plasminogen activator (t-PA) in normal subjects ...
Songting Bai
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Improving 1-Deamino-8-D-Arginine Vasopressin (DDAVP) Challenges in Pediatric/Young Adult Patients With Bleeding Disorders: A Quality Improvement Study

Journal of Pediatric Hematology/Oncology Nursing
Background: Desmopressin (1-deamino-8-D-arginine vasopressin [DDAVP]) has demonstrated efficacy as a treatment option for patients with inherited bleeding disorders.
Michelle Hallam, Amber Pruett, Charmaine Biega, Haley Miller, Tami Davis, Linda Casto, Amy L. Dunn, Vilmarie Rodriguez   +7 more
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Absorption of 1-deamino-8-D-arginine vasopressin from different regions of the gastrointestinal tract in rabbits.

Acta Endocrinologica, 1986
By using a specific radioimmunoassay for 1-deamino-8-D-arginine vasopressin (DDAVP), plasma concentrations were measured in rabbit plasma at various times after intra-gastrointestinal injections.
S. Lundin, H. Vilhardt
semanticscholar   +4 more sources

Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4. [PDF]

Journal of Medicinal Chemistry, 2004
The glutamine(4) residue in [deamino-Cys(1)]arginine vasopressin (dAVP) was replaced by a broad series of aliphatic, aromatic, polar, and charged amino acids to give the following peptides: d[Gly(4)]AVP (1), d[Ala(4)]AVP (2), d[Abu(4)]AVP (3), d[Nva(4 ...
L. Cheng, S. Stoev, M. Manning, S. Derick, A. Peña, Mohamed Slim Ben Mimoun, G. Guillon   +6 more
semanticscholar   +3 more sources

SYNTHESIS AND SOME PHARMACOLOGICAL PROPERTIES OF DEAMINO(4-THREONINE,8-D-ARGININE)VASOPRESSIN AND DEAMINO(8-D-ARGININE)VASOPRESSIN, HIGHLY POTENT AND SPECIFIC ANTIDIURETIC PEPTIDES, AND (8-D-ARGININE)VASOPRESSIN AND DEAMINO-ARGININE-V

Chemischer Informationsdienst, 1976
M. Manning, L. Balaspiri, J. Moehring, J. Haldar, W. Sawyer   +4 more
semanticscholar   +3 more sources