Results 171 to 180 of about 2,208 (222)
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Intranasal Deamino-8-<i>D</i>-Arginine Vasopressin Shortens the Bleeding Time in Uremia
American Journal of Nephrology, 1984Clinical bleeding in uremia is a frequent problem and seems to correlate with a prolonged bleeding time. The vasopressin analog deamino-8-D-arginine vasopressin has been shown to shorten the bleeding time and to decrease clinical bleeding when administered intravenously to uremic patients.
Michael D. Shapiro, Stephen P. Kelleher
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Effects of arginine-8-vasopressin and 1-deamino-8-D-arginine-vasopressin on ACTH secretion in rats.
Endocrinologia experimentalis, 1983The corticotropin-releasing effect of arginine-8-vasopressin (AVP) has been compared to that of 1-deamino-8-D-arginine-vasopressin (dDAVP) in male rats of R-Amsterdam strain. AVP increased the level of ACTH and corticosterone in the peripheral blood in a dose-dependent manner.
László Ferenc+5 more
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The direct action of arginine-vasopressin (AVP) and its deamino-D-arginine analogue (DDAVP) on renin release (RR) has been studied in isolated rat kidneys perfused with an electrolyte solution at constant pressure in a single-pass system. AVP and DDAVP infused at various concentrations (80 to 2100 pg/ml and 80 to 8700 pg/ml, respectively) reduced ...
A. Konrads+3 more
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BIOLOGICAL HALF-LIFE AND ORGAN DISTRIBUTION OF [3H]1-DEAMINO-8-d-ARGININE-VASOPRESSIN IN THE RAT
Journal of Endocrinology, 1981The biological half-life of synthetic, radiochemically pure, biologically active [3H]1-deamino-8-d-arginine-vasopressin (dDAVP) in rats was found to be 5·33 ± 0·28 (s.e.m.) min in the initial, transitional, fast phase and 56·28 ± 3·27 min in the second, slow phase.
László F A+3 more
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Design of Potent and Selective Agonists for the Human Vasopressin V1bReceptor Based on Modifications of [Deamino-Cys]arginine Vasopressin at Position 4 [PDF]
The glutamine(4) residue in [deamino-Cys(1)]arginine vasopressin (dAVP) was replaced by a broad series of aliphatic, aromatic, polar, and charged amino acids to give the following peptides: d[Gly(4)]AVP (1), d[Ala(4)]AVP (2), d[Abu(4)]AVP (3), d[Nva(4)]AVP (4), d[Nle(4)]AVP (5), d[Leu(4)]AVP (6), d[Ile(4)]AVP (7), d[Thi(4)]AVP (8), d[Phe(4)]AVP (9), d ...
Ling Ling Cheng+6 more
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Clinical Pharmacology and Therapeutics, 1981
The response to 1-deamino-8-D-arginine vasopressin (DDAVP), an intranasally administered analogue of vasopressin, was investigated in children and adults with central diabetes insipidus. To assess the action of DDAVP on the distal nephron, cyclic adenosine monophosphate (cAMP) excretion was assayed in urine collected 4 hr before and during four ...
Piers R. Blackett+3 more
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The response to 1-deamino-8-D-arginine vasopressin (DDAVP), an intranasally administered analogue of vasopressin, was investigated in children and adults with central diabetes insipidus. To assess the action of DDAVP on the distal nephron, cyclic adenosine monophosphate (cAMP) excretion was assayed in urine collected 4 hr before and during four ...
Piers R. Blackett+3 more
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Thrombosis Research, 1992
1-Deamino-8 D-arginine vasopressin (DDAVP) has been used effectively to normalize the bleeding time in various hemostatic disorders. In von Willebrand disease the reduction in bleeding time is due to the preferential release of large multimers of von Willebrand factor from endothelial cells.
Marie J. Stuart+2 more
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1-Deamino-8 D-arginine vasopressin (DDAVP) has been used effectively to normalize the bleeding time in various hemostatic disorders. In von Willebrand disease the reduction in bleeding time is due to the preferential release of large multimers of von Willebrand factor from endothelial cells.
Marie J. Stuart+2 more
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Cellular and Molecular Neurobiology, 1988
1. Anterolateral cut (ALC) of the medial basal hypothalamus (MBH) in rats produces an elevation of plasma catecholamine levels, especially of norepinephrine (NE), in unstressed animals and a more pronounced rise of plasma NE levels in response to immobilization (IMO).
Lichardus B+4 more
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1. Anterolateral cut (ALC) of the medial basal hypothalamus (MBH) in rats produces an elevation of plasma catecholamine levels, especially of norepinephrine (NE), in unstressed animals and a more pronounced rise of plasma NE levels in response to immobilization (IMO).
Lichardus B+4 more
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Desmopressin Acetate (1-Deamino-8-D-arginine vasopressin, DDAVP) Response Test
1989Exogenously administered desmopressin acetate (1-deamino-S-D-arginine vasopressin, DDAVP) fails to lessen the diuresis in either congenital or acquired nephrogenic diabetes insipidus. These disorders are characterised by renal tubular end-organ resistance to vasopressin, thus differentiating them from hypothalamic/pituitary diabetes insipidus, in which
P. T. Lascelles, D. Donaldson
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Acta Endocrinologica, 1986
Abstract. By using a specific radioimmunoassay for 1-deamino-8-D-arginine vasopressin (DDAVP), plasma concentrations were measured in rabbit plasma at various times after intra-gastrointestinal injections. Five anatomically distinct regions were employed to administer the peptide, namely: the stomach, the duodenum, the mid-part of the ileum, the ileo ...
Stefan Lundin, Hans Vilhardt
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Abstract. By using a specific radioimmunoassay for 1-deamino-8-D-arginine vasopressin (DDAVP), plasma concentrations were measured in rabbit plasma at various times after intra-gastrointestinal injections. Five anatomically distinct regions were employed to administer the peptide, namely: the stomach, the duodenum, the mid-part of the ileum, the ileo ...
Stefan Lundin, Hans Vilhardt
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