Results 161 to 170 of about 4,365,723 (297)

Immunoexpression of programmed death receptor 1 and its ligands in oral cavity squamous cell carcinoma. [PDF]

Med Oral Patol Oral Cir Bucal
Anjos RS, Barros EF, Firmo AC, Nonaka CF, Carvalho MD, Godoy GP.   +5 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

CMTM6 suppresses cell-surface expression of death receptor FAS in mice but not in humans. [PDF]

EMBO Rep
Semberova T, Pribikova M, Cimermanova V, Trivic T, Haderbache R, Paprckova D, Christen L, Kissiova H, Stepanek O, Draber P.   +9 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

A non-complement role for C1R rewires integrin and death-receptor signaling to drive renal cancer metastasis. [PDF]

Mol Cancer
Wei H, Li S, Zhu S, Xu C, Wang Y, Li Z, Guan Y, Li J, Jiang R, Ge X, Yi T, Xu X, Xie Y, Tian J, Piao Y, Zhang P, Quan C, Jin X.   +17 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Influence of Different Death Receptor Signaling Pathways on Apoptosis of <i>Eimeria tenella</i> Host Cells. [PDF]

Curr Issues Mol Biol
Xu Z, Yu X, Ma J, Yu Y.
europepmc   +1 more source

Death receptor 5 promotes tumor progression in gastric cancer. [PDF]

FEBS Open Bio, 2023
Chen J, Li L, Huangfu L, Du H, Ji X, Xing X, Ji J.   +6 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Antitumor Activity of Death Receptor 5-Targeted Camptothecin-Loaded Nanoparticles in Murine Syngeneic Models. [PDF]

Biomacromolecules
Boland AJ, Greene MK, Herron ÚM, Johnston MC, Smyth P, Yagita H, Longley DB, Scott CJ.   +7 more
europepmc   +1 more source