Results 1 to 10 of about 555,297 (117)

Terahertz Waves Trigger Apoptosis in Cutaneous Squamous Cell Carcinoma via Apoptosis-Inducing Factor Mediated Mitochondrial Pathway [PDF]

Cells
Background: Terahertz (THz) waves exhibit both photon-like and electron-like properties, showing emerging potential in biomedical applications. Cutaneous squamous cell carcinoma (CSCC) is one of the most common skin tumors. Studies have reported that THz
Liu Sun, Wenxia Wang, Shuocheng She, Lei Wang, Jinwu Zhao, Pandeng Hou, Mingxia He   +6 more
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Deoxynivalenol Induces Caspase-8-Mediated Apoptosis through the Mitochondrial Pathway in Hippocampal Nerve Cells of Piglet

Toxins, 2021
Deoxynivalenol (DON) is a common trichothecene mycotoxin found worldwide. DON has broad toxicity towards animals and humans. However, the mechanism of DON-induced neurotoxicity in vitro has not been fully understood.
Li Cao, Yunjing Jiang, Lei Zhu, Wei Xu, Xiaoyan Chu, Yafei Zhang, Sajid Ur Rahman, Shibin Feng, Yu Li, Jinjie Wu, Xichun Wang   +10 more
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Structure Identification of Euphorbia Factor L3 and Its Induction of Apoptosis through the Mitochondrial Pathway

Molecules, 2011
In this article, we have focused on the structure identification of Euphorbia factor L3 belonging to the lathyrane diterpenoids isolated from Caper Euphorbia Seed.
Hui Zhang, Li-Wu Fu, Xiao-Kun Wang, Xiao-Qin Zhao, Yan-Jun Mi, Fang Wang, Li-Sheng Zheng, Yong-Ju Liang, Hu-Biao Chen, Jian-Ye Zhang   +9 more
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Feiyanning Formula Induces Apoptosis of Lung Adenocarcinoma Cells by Activating the Mitochondrial Pathway

Frontiers in Oncology, 2021
Feiyanning formula (FYN) is a traditional Chinese medicine (TCM) prescription used for more than 20 years in the treatment of lung cancer. FYN is composed of Astragalus membranaceus, Polygonatum sibiricum, Atractylodes macrocephala, Cornus officinalis ...
Li-Min Zhu, Hai-Xia Shi, Masahiro Sugimoto, Kenjiro Bandow, Hiroshi Sakagami, Shigeru Amano, Hai-Bin Deng, Qing-Yu Ye, Yun Gai, Xiao-Li Xin, Zhen-Ye Xu   +10 more
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Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats

Annals of Agricultural and Environmental Medicine, 2020
Introduction Chlorpyrifos (CPF) is a organophosphate insecticide widely used in agriculture with attendant adverse health outcomes. Chronic exposure to CPF induces oxidative stress and elicits harmful effects, including hepatic dysfunction.
Zhi-ming Xun, Fei Xie, Peng-xiang Zhao, Meng-yu Liu, Zhi-yuan Li, Jian-mei Song, Xian-min Kong, Xue-mei Ma, Xiao-yang Li   +8 more
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Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells [PDF]

International Journal of Ophthalmology, 2019
AIM: To explore the effect of parthenolide (PTL) on human uveal melanoma (UM) cells (C918 and SP6.5 cells) and its molecular mechanism. METHODS: Carboxyfluorescein succinimidyl amino ester (CFSE) assays and cell counting kit-8 (CCK-8) were performed to ...
Song-Tian Che, Li Bie, Xu Li, Hui Qi, Peng Yu, Ling Zuo   +5 more
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Hesperetin Promotes Cisplatin−Induced Apoptosis of Gastric Cancer In Vitro and In Vivo by Upregulating PTEN Expression

Frontiers in Pharmacology, 2020
As one of the most common malignant gastrointestinal tumors, gastric cancer (GC) has a high incidence and poor prognosis. Cisplatin (DDP) is often used as chemotherapy for advanced GC; however, the high incidence of drug resistance remains a problem. The
Pengzhan He, Pengzhan He, Pengzhan He, Jingjing Ma, Yinghui Liu, Yinghui Liu, Yinghui Liu, Huan Deng, Huan Deng, Huan Deng, Weiguo Dong   +10 more
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Laminarin Induces Apoptosis of Human Colon Cancer LOVO Cells through a Mitochondrial Pathway

Molecules, 2012
Many scientific studies have shown that laminarin has anti-tumor effects, but the anti-tumor mechanism was unclear. The purpose of this study was to investigate the effect of laminarin on the induction of apoptosis in human colon cancer LOVO cells and ...
He Zhang, Yu Bin Ji, Chen Feng Ji
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The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head

Frontiers in Pharmacology, 2020
Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is a frequently occurring type of nontraumatic osteonecrosis. A failure of the timely treatment can eventually result in the collapse of the subchondral bone structure.
Zijian Yan, Zijian Yan, Zijian Yan, Jingdi Zhan, Jingdi Zhan, Jingdi Zhan, Weihui Qi, Weihui Qi, Weihui Qi, Jian Lin, Yijiang Huang, Xinghe Xue, Xiaoyun Pan   +12 more
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Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway

Frontiers in Veterinary Science, 2021
Canine breast cancer (CBC) is the most common spontaneous tumor in intact female dogs, especially in developing countries. The effective anti-tumor agents or therapies for the clinical treatment of CBC are still in need.
Zhaoyan Lin, Zixiang Lin, Ying Zhao, Nan Cheng, Di Zhang, Jiahao Lin, Hong Zhang, Degui Lin   +7 more
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