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Death receptor‐induced cell death in prostate cancer

Journal of Cellular Biochemistry, 2003
AbstractProstate cancer mortality results from metastasis and is often coupled with progression from androgen‐dependent to androgen‐independent growth. Unfortunately, no effective treatment for metastatic prostate cancer increasing patient survival is available. The absence of effective therapies reflects in part a lack of knowledge about the molecular
Natalya V, Guseva   +3 more
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Structural Studies of Death Receptors

2014
This chapter describes reports of the structural characterization of death ligands and death receptors (DRs) from the tumor necrosis factor (TNF) and TNF receptor families. The review discusses the interactions of these proteins with agonist ligands, inhibitors, and downstream signaling molecules.
openaire   +2 more sources

The Death Receptor Pathway

2009
The TNF receptor superfamily is a large group of membrane-associated receptors characterized by structural similarities in their extracellular and intracellular domains. A subgroup of these receptors, the so-called death receptors, shares an intracellular motif termed the death domain.
Maria Eugenia Guicciardi   +1 more
openaire   +1 more source

Avoiding The Death Receptor

Chemical & Engineering News Archive, 2013
Receptors for the neurotransmitter serotonin are distributed throughout nearly every organ system in the body, and they are the targets of drugs to treat innumerable problems, including depression, migraines, and obesity. Drug designers do their best to craft molecules that zero in on individual serotonin receptors (also known as 5-HTs).
openaire   +1 more source

Critical care management of chimeric antigen receptor T-cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Sandrine Valade   +2 more
exaly  

The Death Receptor Pathway of Apoptosis

Cold Spring Harbor Perspectives in Biology, 2022
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THE DEATH RECEPTORS

2010
KLAUS SCHULZE-OSTHOFF, MARCUS E PETER
openaire   +1 more source

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