Results 61 to 70 of about 589,147 (148)

Scarred by a death receptor [PDF]

The Journal of Cell Biology, 2007
![Graphic][1] The fibrin (red) that blocks nerve healing is degraded when p75NTR isn't around (right) to dampen tPA levels. Even when it's not killing, a death receptor still finds ways to inflict damage. On page [1119][2], Sachs et al.
openaire   +1 more source

PTPN23-dependent ESCRT machinery functions as a cell death checkpoint

Nature Communications
Cell death plasticity is crucial for modulating tissue homeostasis and immune responses, but our understanding of the molecular components that regulate cell death pathways to determine cell fate remains limited.
Dongyan Song, Yuxin Cen, Zhe Qian, Xiaoli S. Wu, Keith Rivera, Tse-Luen Wee, Osama E. Demerdash, Kenneth Chang, Darryl Pappin, Christopher R. Vakoc, Nicholas K. Tonks   +10 more
doaj   +1 more source

Pattern Recognition Receptors and the Host Cell Death Molecular Machinery

Frontiers in Immunology, 2018
Pattern Recognition Receptors (PRRs) are proteins capable of recognizing molecules frequently found in pathogens (the so-called Pathogen-Associated Molecular Patterns—PAMPs), or molecules released by damaged cells (the Damage-Associated Molecular ...
Gustavo P. Amarante-Mendes, Gustavo P. Amarante-Mendes, Sandy Adjemian, Sandy Adjemian, Laura Migliari Branco, Laura Migliari Branco, Larissa C. Zanetti, Ricardo Weinlich, Karina R. Bortoluci, Karina R. Bortoluci   +9 more
doaj   +1 more source

HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer. [PDF]

PLoS Pathog, 2023
Khalil MI, Yang C, Vu L, Chadha S, Nabors H, Welbon C, James CD, Morgan IM, Spanos WC, Pyeon D.   +9 more
europepmc   +1 more source

Amyloid Beta Oligomers Activate Death Receptors and Mitochondria-Mediated Apoptotic Pathways in Cerebral Vascular Smooth Muscle Cells; Protective Effects of Carbonic Anhydrase Inhibitors. [PDF]

Cells, 2023
Anzovino A, Canepa E, Alves M, Lemon NL, Carare RO, Fossati S.   +5 more
europepmc   +1 more source

Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies. [PDF]

Oncogenesis, 2023
Favaro F, Both D, Derks IAM, Spaargaren M, Muñoz-Pinedo C, Eldering E.   +5 more
europepmc   +1 more source

Combining chemotherapeutic agents and netrin‐1 interference potentiates cancer cell death

EMBO Molecular Medicine, 2013
The secreted factor netrin‐1 is upregulated in a fraction of human cancers as a mechanism to block apoptosis induced by netrin‐1 dependence receptors DCC and UNC5H. Targeted therapies aiming to trigger tumour cell death via netrin‐1/receptors interaction
Andrea Paradisi, Marion Creveaux, Benjamin Gibert, Guillaume Devailly, Emeline Redoulez, David Neves, Elsa Cleyssac, Isabelle Treilleux, Christian Klein, Gerhard Niederfellner, Philippe A. Cassier, Agnès Bernet, Patrick Mehlen   +12 more
doaj   +1 more source

BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma. [PDF]

J Biol Chem, 2021
Ishii Y, Kolluri KK, Pennycuick A, Zhang X, Nigro E, Alrifai D, Borg E, Falzon M, Shah K, Kumar N, Janes SM.   +10 more
europepmc   +1 more source

Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation. [PDF]

BMC Cancer, 2022
Lohberger B, Glänzer D, Kaltenegger H, Eck N, Leithner A, Bauer R, Kretschmer N, Steinecker-Frohnwieser B.   +7 more
europepmc   +1 more source

Corrigendum: Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL. [PDF]

Front Cell Dev Biol, 2021
Artykov AA, Yagolovich AV, Dolgikh DA, Kirpichnikov MP, Trushina DB, Gasparian ME.   +5 more
europepmc   +1 more source