Results 101 to 110 of about 589,147 (148)

Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death. [PDF]

Mol Cancer Ther, 2016
Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, Diaz PW, Matsuzawa S, Horowitz M, Horowitz L, Bhatt RR, Reed JC.   +15 more
europepmc   +1 more source

Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors. [PDF]

J Biol Chem, 2016
Sung B, Park B, Yadav VR, Aggarwal BB.
europepmc   +1 more source

Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients. [PDF]

J Transl Med, 2017
Schiza A, Wenthe J, Mangsbo S, Eriksson E, Nilsson A, Tötterman TH, Loskog A, Ullenhag G.   +7 more
europepmc   +1 more source

Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells. [PDF]

Molecules, 2018
Gao Y, Yin J, Rankin GO, Chen YC.
europepmc   +1 more source

Retraction: ROS and CHOP Are Critical for Dibenzylideneacetone to Sensitize Tumor Cells to TRAIL through Induction of Death Receptors and Downregulation of Cell Survival Proteins. [PDF]

Cancer Res, 2018
europepmc   +1 more source

The signaling and regulatory functions of dying cells and cell corpses. [PDF]

Commun Biol
Zhang G, Liu J, Li W, Wang B, Feng H, Cui T, Pan T, Chen D, Xiong Y.   +8 more
europepmc   +1 more source

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Apoptosis induced by death receptors

Pharmaceutica Acta Helvetiae, 2000
Death receptors belong to the TNF receptor family and are characterised by an intracellular death domain that serves to recruit adapter proteins such as TRADD and FADD and cysteine proteases such as Caspase-8. Activation of Caspase-8 on the aggregated receptor leads to apoptosis. Triggering of death receptors is mediated through the binding of specific
Pascal Schneider, J Tschopp
exaly   +4 more sources

Death Receptors: Signaling and Modulation

Science, 1998
REVIEW Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors, on their surface.
Vishva Dixit, Avi Ashkenazi
exaly   +3 more sources

Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors

Biochemical and Biophysical Research Communications, 2005
Death receptors (DRs) can induce apoptosis by oligomerization with TRAIL, whereas death decoy receptors (DcRs) cannot, due to their lack of functional intracellular death domains. However, it is not known whether DRs and DcRs can interact with one another to form oligomeric complexes prior to TRAIL binding.
Myung-Hee Kwon, Yong-Sung Kim
exaly   +3 more sources

The Death Receptors

1999
In recent years apoptosis, also called programmed cell death, has been recognized to be the physiological way for a nucleated animal cell to die. Apoptosis takes care of unwanted, injured or virus-infected cells (Farber 1994; Collins 1995). Autoreactive T and B cells that are produced by the immune system by the millions every day are also eliminated ...
Peter, M. E., Scaffidi, C., Medema, J. P., Kischkel, F., Krammer, P. H.   +4 more
openaire   +4 more sources