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The Death Receptor Pathway

2009
The TNF receptor superfamily is a large group of membrane-associated receptors characterized by structural similarities in their extracellular and intracellular domains. A subgroup of these receptors, the so-called death receptors, shares an intracellular motif termed the death domain.
Maria Eugenia Guicciardi   +1 more
openaire   +1 more source

Avoiding The Death Receptor

Chemical & Engineering News Archive, 2013
Receptors for the neurotransmitter serotonin are distributed throughout nearly every organ system in the body, and they are the targets of drugs to treat innumerable problems, including depression, migraines, and obesity. Drug designers do their best to craft molecules that zero in on individual serotonin receptors (also known as 5-HTs).
openaire   +1 more source

Death receptors and their ligands

2000
The identification and description of an intrinsic program of regulated cellular suicide or apoptosis was originally obtained from morphological analyses in developmental biology (76, 77). This program exists in all multicellular organisms, and genetic analyses in the nematode Caenorhabditis elegans identified three ced-genes (for C.
Jürgen Holtz, Dorothea Darmer
openaire   +1 more source

The Death Receptor Pathway of Apoptosis

Cold Spring Harbor Perspectives in Biology, 2022
openaire   +2 more sources

Death Receptors

2007
Sharmila Shankar, Rakesh K. Srivastava
openaire   +1 more source

Cell death‐independent activities of the death receptors CD95, TRAILR1, and TRAILR2

FEBS Journal, 2017
Daniela Siegmund   +2 more
exaly  

MicroRNAs as regulators of death receptors signaling

Cell Death and Differentiation, 2009
M Garofalo   +2 more
exaly  

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