Overcoming Challenges in Small-Ring Transfer: Direct Decarboxylative Hydroalkylation of Alkenes via Iron-Thiol Catalysis. [PDF]
Angew Chem Int Ed EnglHerein, we present a catalytic approach for the direct decarboxylation of challenging CF3‐cyclopropyl and cyclobutyl carboxylic acids using cooperative iron‐thiol catalysis. This strategy enables the efficient generation of valuable radicals that can be incorporated into activated and unactivated alkenes, offering access to elusive chemical space ...
Giri R +5 more
europepmc +3 more sources
Entry to 2-aminoprolines via electrochemical decarboxylative amidation of N‑acetylamino malonic acid monoesters [PDF]
Beilstein Journal of Organic ChemistryThe electrochemical synthesis of 2-aminoprolines based on anodic decarboxylation–intramolecular amidation of readily available N-acetylamino malonic acid monoesters is reported. The decarboxylative amidation under Hofer–Moest reaction conditions proceeds
Olesja Koleda +5 more
doaj +2 more sources
Direct reversible decarboxylation from stable organic acids in dimethylformamide solution
Science, 2020 Simple swaps of CO2 The loss of carbon dioxide (CO2) from carboxylic acids is a common reaction in both biochemical and synthetic contexts, but it has generally involved catalysis or prolonged heating. Kong et al.
D. Kong +4 more
semanticscholar +1 more source
Acta Medica, 2000 Decarboxylation of aromatic amino acid in mammalian tissues is catalyzed by aromatic amino acid decarboxylase (EC. 4.1.1.28, AAD). The enzyme differs in its affinity to individual aromatic amino acids, the best substrates being 3,4-dihydroxyphenylalanine
Jaroslav Dršata, Eliška Marklová
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Phosphoenolpyruvate Carboxykinase Is Involved in the Decarboxylation of Aspartate in the Bundle Sheath of Maize [PDF]
, 1999 We recently showed that maize (Zea mays L.) leaves contain appreciable amounts of phosphoenolpyruvate carboxykinase (PEPCK; R.P. Walker, R.M. Acheson, L.I. Técsi, R.C. Leegood [1997] Aust J Plant Physiol 24: 459–468).
Chen, Z. +3 more
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Synthesis of Hydrophobically and Electrostatically Modified Polyacrylamides and Their Catalytic Effects on the Unimolecular Decarboxylation of 6-Nitrobenzisoxazole-3-carboxylate Anion [PDF]
, 1995 A series of hydrophobically and electrostatically modified polyacrylamides (Copol(AM-C12)) has been synthesized by radical-initiated copolymerization of acrylamide with n-dodecylmethyldiallylammonium bromide as the hydrophobe in aqueous solution using ...
Engberts, Jan B.F.N.,, Wang, Guang-Jia,
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Molecules, 2021 Isolation of the therapeutic cannabinoid compounds from Cannabis Sativa L. (C. Sativa) is important for the development of cannabis-based pharmaceuticals for cancer treatment, among other ailments.
Yannick Nuapia +4 more
doaj +1 more source
A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase [PDF]
, 2013 Biotin-dependent enzymes catalyze carboxyl transfer reactions by efficiently coordinating multiple reactions between spatially distinct active sites. Pyruvate carboxylase (PC), a multifunctional biotin-dependent enzyme, catalyzes the bicarbonate- and ...
Lietzan, Adam D, Maurice, Martin St.
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Impact of sunlight irradiation on CvFAP photodecarboxylation
Frontiers in Catalysis, 2023 A visible-light-driven photocatalytic decarboxylation of palmitic acid and related fatty acids is described in this study. Remarkable decarboxylation rates have been observed with full conversion in less than 20 min.
Alexandre S. França +6 more
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Biocatalytic Route to Chiral Precursors of β-Substituted-γ-Amino Acids [PDF]
, 2011 In this work, we utilized commercial lipases (from Thermomyces lanuginosa, Rhizopus delemar, and Mucor miehei) as biocatalysts for the efficient synthesis of precursors of β-substituted-γ-amino acids.
Martinez, Carlos A., Mukherjee, Herschel
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