Results 101 to 110 of about 10,347,709 (335)

DECENT WORK AND COFFEE SECTOR: ARE THE COFFEE ESTATES IN KENYA COMPLYING WITH DECENT WORK IN PRODUCTION AND PRIMARY PROCESSING?

Apstract: Applied Studies in Agribusiness and Commerce
Coffee plays a big role in Kenya, it contributes to 30 percent of agricultural jobs and country’s exports. However, casual workers within coffee estates still get challenging employment conditions including long working hours, unfair wages, limited ...
Joseph Munyentwari Mbuta, Bett K Hillary, Rebecca Jerop   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Decent Work and Representations of Work among Unskilled and Low-Skilled Emerging Adults in France

Revista de Psicología, 2023
The current labor market context is characterized by a diversification of forms of employment, a transformation of work organizations and a singularization of career paths.
Soazig Disquay-Perot, Laurence Cocandeau-Bellanger, Angel Egido-Portela, Nadia Baatouche, Nathalie Prudhomme, Emmanuelle Vignoli   +5 more
doaj  

Resilient generation: supporting young people’s prospects for decent work in the drylands of East and West Africa

, 2021
Mairi Dupar, Emma Lovell, Olivia Walmsley, Vidya Diwakar, Camille Balcou, Beda Tesfaye, Krishna Vaidehi   +6 more
openalex   +1 more source

The Relationship Between Sex Discrimination and Job and Life satisfaction in Female Employees: The Mediating Effects of Work Volition and Decent Work [PDF]

, 2021
Seran Lee, Ki-Hak Lee
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A OIT, o Ministério do Trabalho e Emprego, e o Ministério Público do Trabalho: o “trabalho decente” no Brasil

Ciências Sociais Unisinos, 2015
This paper refers to a broader research focused on the trajectory of the International Labour Organization (ILO) in Brazil. As an important institution in the Brazilian labor scene, the ILO has currently excelled in projects that move around the idea of ...
Márcia Regina Barroso
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source