Results 61 to 70 of about 10,347,709 (335)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Decent work, financial inclusion, and economic growth: Analysis under the SDG 8
We investigate the potential influence of decent work and financial inclusion on economic growth, aligning our analysis with the United Nations Sustainable Development Goal 8 (SDG 8).
Chokri Zehri +4 more
semanticscholar +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Domestic Work: Challenges for Decent Work
This article presents an overview of the situation of the domestic workers and focuses on some issues related to its dimension in the world and in Brazil, to their conditions of work and its importance to the labor market and to the households.
Solange Sanches
doaj
Decent Work in a Changing Climate
Climate change is placing increased pressures on workers, including their health, working conditions, and economic outcomes. Whilst efforts by international governance mechanisms and governments espouse the need to achieve decent work, in reality, the ...
Bethany Jackson +2 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Paradoxes of Decent Work in Context: A Cultural Political Economy Perspective
Scientific discourses of decent work can be roughly grouped into two main lines of interpretation. The first, optimistic line sees the International Labour Organisation’s (ILO) decent work agenda as indicative of counter-hegemonic forces successfully ...
Felix Hauf
doaj +1 more source

