Results 71 to 80 of about 1,927 (208)
Ciências Sociais Unisinos, 2015 This paper refers to a broader research focused on the trajectory of the International Labour Organization (ILO) in Brazil. As an important institution in the Brazilian labor scene, the ILO has currently excelled in projects that move around the idea of ...
Márcia Regina Barroso
doaj
Decent work perception among PICU nurses: current status and influencing factors
BMC NursingBackground Decent work perception significantly influences an individual’s professional decisions and choices. This survey aimed to evaluate the current status and influencing factors of decent work perception among pediatric intensive care unit (PICU ...
Min Cao +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Humanities & Social Sciences CommunicationsDecent work was proposed by International Labour Organization (ILO) as an institutional measure to address challenges faced by labor in the current competitive dynamic labor market. This study aims to investigate the impact of “decent work” dimensions on
Rasha S. Hassan +2 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Exploring decent work among domestic workers in South Africa: A qualitative perspective
SA Journal of Industrial PsychologyOrientation: Experiences of decent working conditions for domestic workers within the International Labour Organization’s (ILO) decent work standards. Research purpose: Explore how domestic workers in South Africa experience decent work and address gaps ...
Naheedah M. Collins, Karolina Łaba
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source