The biology of decorin in the tumor microenvironment [PDF]
Decorin is a ubiquitous secreted small-leucine rich proteoglycan associated with all major collagen-rich matrices. Initially described for its roles in maintaining the structural integrity of various organs and in collagen fibrillogenesis, decorin has ...
Buraschi, Simone
core
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要： 【目的】 阐明ＢＭＰ２是否参与了Ｄｅｃｏｒｉｎ诱导的血管平滑肌细胞（ＶＳＭＣ）钙化。【方法】 本研究采用人血管平滑肌细胞钙化体外模型，用腺病毒载体过表达Ｄｅｃｏｒｉｎ，检测骨相关蛋白ＢＭＰ２、Ｍｓｘ２、Ｏｓｔｅｒｉｘ的表达和细胞钙化程度。观察抑制或增加ＢＭＰ２信号对Ｄｅｃｏｒｉｎ诱导的血管平滑肌细胞钙化和Ｍｓｘ２、Ｏｓｔｅｒｉｘ表达的影响。【结果】Ｄｅｃｏｒｉｎ能促进人血管平滑肌细胞钙化，同时上调ＢＭＰ２、Ｍｓｘ２、Ｏｓｔｅｒｉｘ的表达水平。抑制ＢＭＰ２能减轻Ｄｅｃｏｒｉｎ诱导的细胞钙化 ...
doaj
Recombinant Decorin Glycoforms [PDF]
Journal of Biological Chemistry, 1996 Priya Ramamurthy +2 more
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Systemic clinical-grade recombinant decorin reduces disease burden and fibrosis in advanced recessive dystrophic epidermolysis bullosa. [PDF]
Mol Ther AdvGretzmeier C +12 more
europepmc +1 more source
Synergistic antitumor efficacy of a decorin-carrying oncolytic adenovirus combined with chemotherapy in pancreatic cancer. [PDF]
Front OncolChen J +4 more
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Exercise-secreted antitumor myokines: mechanistic insights and translational potential. [PDF]
Front Sports Act LivingHan S +6 more
europepmc +1 more source
Determination of Dental Lesions in Dairy Cattle and Immunochemical Detection of the Biomarker Decorin in Gingival Crevicular Fluid of Dairy Cattle. [PDF]
Vet Med SciAvci N.
europepmc +1 more source
Reduction of angiogenesis in chorioallantoic membrane xenografted hepatocellular carcinomas by treatment with a decorin-expressing herpes simplex virus vector. [PDF]
Virol JFrejborg F +6 more
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Endothelial PAI-1 Drives Lead-Induced Cerebral Amyloid Angiopathy via Activation of C3<sup>+</sup> Decorin<sup>+</sup> A1-like Astrocytes. [PDF]
Biology (Basel)Gu H, Luo C, Du Y.
europepmc +1 more source