Results 101 to 110 of about 22,245,271 (149)

Candida albicans Cells Lacking AP‐2 Have Defective Hyphae and Are Avirulent Despite Increased Host Uptake and Intracellular Proliferation in Macrophages

Molecular Microbiology, Volume 125, Issue 1, Page 1-12, January 2026.
Mutation of exocytic cargo adapter apm4Δ/Δ results in reduced virulence of Candida albicans during infection despite promoting intracellular growth in macrophages. ABSTRACT Candida albicans is a commensal microbe and opportunistic human pathogen. Candida yeast are recognized and taken up by macrophages via phagocytosis.
Stella Christou, Shannon Evans, Harriet Knafler, Iwona Smaczynska‐de Rooij, Kathryn R. Ayscough, Simon A. Johnston   +5 more
wiley   +1 more source

Molecular Cloning of Human Dectin-2 [PDF]

Journal of Investigative Dermatology, 2004
Kanazawa, Nobuo, Tashiro, Kei, Inaba, Kayo, Lutz, Manfred B., Miyachi, Yoshiki   +4 more
openaire   +2 more sources

The CARD9-Associated C-Type Lectin, Mincle, Recognizes La Crosse Virus (LACV) but Plays a Limited Role in Early Antiviral Responses against LACV

Viruses, 2019
La Crosse virus (LACV) is a mosquito-transmitted arbovirus and the main cause of virus-mediated neurological diseases in children. To date, little is known about the role of C-type lectin receptors (CLRs)—an important class of pattern recognition ...
João T. Monteiro, Kathleen Schön, Tim Ebbecke, Ralph Goethe, Jürgen Ruland, Wolfgang Baumgärtner, Stefanie C. Becker, Bernd Lepenies   +7 more
doaj   +1 more source

Inhibition of Dectin-1 Alleviates Neuroinflammatory Injury by Attenuating NLRP3 Inflammasome-Mediated Pyroptosis After Intracerebral Hemorrhage in Mice: Preliminary Study Results

Journal of Inflammation Research, 2022
Zhiquan Ding1 *, Zhenzhong Zhong1 *, Jun Wang1 *, Run Zhang,2 Jinlian Shao,3 Yulong Li,1 Guiwei Wu,1 Huiru Tu,1 Wen Yuan,4 Haitao Sun,1,5 Qinghua Wang1,3 1Neurosurgery Center, Department of Neurotrauma and Neurocritical Care Medicine ...
Ding Z, Zhong Z, Wang J, Zhang R, Shao J, Li Y, Wu G, Tu H, Yuan W, Sun H, Wang Q   +10 more
doaj  

Retracted: Effects of the Dectin-2/TNF-α Pathway on Ventricular Arrhythmia after Acute Myocardial Infarction in Mice. [PDF]

Evid Based Complement Alternat Med, 2023
And Alternative Medicine EC.
europepmc   +1 more source

The response of human macrophages to β-glucans depends on the inflammatory milieu.

PLoS ONE, 2013
Backgroundβ-glucans are fungal cell wall components that bind to the C-type lectin-like receptor dectin-1. Polymorphisms of dectin-1 gene are associated with susceptibility to invasive fungal infection and medically refractory ulcerative colitis.
Cristina Municio, Yolanda Alvarez, Olimpio Montero, Etzel Hugo, Mario Rodríguez, Esther Domingo, Sara Alonso, Nieves Fernández, Mariano Sánchez Crespo   +8 more
doaj   +1 more source

Effect of a period of intense functional training on IL-10, Dectin-1, and IL-1Ra in prediabetic obese women [PDF]

Medical Laboratory Journal
Background: Obesity and prediabetes are associated with chronic low-grade inflammation, and macrophage-related markers such as IL-10, Dectin-1, and IL-1Ra play a key role in modulating inflammatory responses.
Maryam Enshaei Mojarad, Hajar Abbaszadeh, Parvin Farzanegi   +2 more
doaj  

Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions. [PDF]

Diab Vasc Dis Res, 2020
Thiem K, Hoeke G, Zhou E, Hijmans A, Houben T, Boels MG, Mol IM, Lutgens E, Shiri-Sverdlov R, Bussink J, Kanneganti TD, Boon MR, Stienstra R, Tack CJ, Rensen PC, Netea MG, Berbée JF, van Diepen JA.   +17 more
europepmc   +1 more source

Dectin-1通过巨噬细胞极化影响STEMI的机制研究

Zhongguo shiyan zhenduanxue
目的 探究Dectin-1通过巨噬细胞极化影响STEMI的机制研究。方法 将45只SPF级SD大鼠随机分为假手术组(n=15)、模型组(n=15)、si-Dectin-1组(n=15),模型组与si-Dectin-1组分别通过尾静脉注射NC-质粒和si-Dectin质粒，2周后建立ST段抬高型心肌梗死(ST-Segment Elevation Myocardial Infarction, STEMI)模型，2周后分离心脏组织，qPCR检测心脏组织Dectin-1表达水平，TTC染色检测心肌坏死面积 ...
孙倩, 苏艳, 张雅兰, 李晓林
doaj  

Dectin-1通过巨噬细胞极化影响STEMI的机制研究 附视频

Zhongguo shiyan zhenduanxue
目的 探究Dectin-1通过巨噬细胞极化影响STEMI的机制研究。方法 将45只SPF级SD大鼠随机分为假手术组(n=15)、模型组(n=15)、si-Dectin-1组(n=15),模型组与si-Dectin-1组分别通过尾静脉注射NC-质粒和si-Dectin质粒，2周后建立ST段抬高型心肌梗死(ST-Segment Elevation Myocardial Infarction, STEMI)模型，2周后分离心脏组织，qPCR检测心脏组织Dectin-1表达水平，TTC染色检测心肌坏死面积 ...
doaj   +2 more sources