Results 91 to 100 of about 12,249 (194)

Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1.

PLoS ONE, 2017
Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection.
Naomi M Walsh, Marcel Wuthrich, Huafeng Wang, Bruce Klein, Christina M Hull   +4 more
doaj   +1 more source

TLR-4 Cooperates with Dectin-1 and Mannose Receptor to Expand Th17 and Tc17 Cells Induced by Paracoccidioides brasiliensis Stimulated Dendritic Cells

Frontiers in Microbiology, 2015
The concomitant use of diverse Pattern Recognition Receptors (PRRs) by innate immune cells can result in synergistic or inhibitory activities that profoundly influence anti-microbial immunity.
Vera Lucia Garcia Calich, Flavio Vieira Loures, Eliseu F. Araujo, Claudia eFeriotti, Silvia B. Bazan   +4 more
doaj   +1 more source

Probiotic‐based strategies in vulvovaginal candidiasis management: A comprehensive review of mechanisms and future directions

Interdisciplinary Medicine, EarlyView.
This review focuses on vulvovaginal candidiasis (VVC), examining its epidemiology, the pathogenesis of Candida albicans, and its relationships with vaginal microbiota. It comprehensively reviews probiotic‐based management strategies and their mechanisms of action, and concludes by discussing current limitations, challenges and future research ...
Tong Chen, Yuwei Wu, Ya Chen, Ying Li, Hui Zhao, Lei Wu, He Gao, Tong Jiang, Xiaohong Wang, Moutong Chen, Jumei Zhang, Xinqiang Xie, Tingting Liang, Qingping Wu   +13 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Immune responses to airborne fungi and non-invasive airway diseases. [PDF]

, 2014
Inhalation of fungal particles is a ubiquitous way of exposure to microorganisms during human life; however, this exposure may promote or exacerbate respiratory diseases only in particular exposure conditions and human genetic background.
Niculita-Hirzel, Hélène, Roger, Thierry, Vacher, Gaëlle   +2 more
core   +1 more source

The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus.

PLoS Pathogens, 2005
Alveolar macrophages represent a first-line innate host defense mechanism for clearing inhaled Aspergillus fumigatus from the lungs, yet contradictory data exist as to which alveolar macrophage recognition receptor is critical for innate immunity to A ...
Chad Steele, Rekha R Rapaka, Allison Metz, Shannon M Pop, David L Williams, Siamon Gordon, Jay K Kolls, Gordon D Brown   +7 more
doaj   +2 more sources

The Role of Dectin-1-Mediated M1 Macrophage Polarization in Cerebral Ischemia-Reperfusion Injury

Emergency Medicine International, 2021
Introduction. The advances in cerebral ischemia treatment have resulted in a larger proportion of patients get the benefits of rebuilding blood flow to the brain. Then, ischemia-reperfusion injury has emerged as a new essential problem. Dectin-1 plays an
Chen Zongyun, Lin Bixia, Ding Fadian, Hong Xiaoping, Chen Hongbin, Deng Yu, Liu Qicai, Ye Xiaoyi, Zeng Kai   +8 more
doaj   +1 more source

Emerging IL-12 family cytokines in the fight against fungal infections [PDF]

, 2018
Invasive fungal infections cause approximately 1.5 million deaths per year worldwide and are a growing threat to human health. Current anti-fungal therapies are often insufficient, therefore studies into host-pathogen interactions are critical for the ...
Acosta-Rodriguez, Aggarwal, Aiysha Thompson, Altare, Apetoh, Ashman, Awasthi, Bacon, Balish, Bardel, Batten, Batten, Beadling, Bedke, Boisson, Bonifazi, Bourgeois, Carrion Sde, Cenci, Cenci, Cenci, Chen, Clement, Collison, Collison, Collison, Conti, Conti, Cooper, de Beaucoudrey, De Luca, Delsing, Depner, Devergne, Devergne, Dixon, Drewniak, Duan, Egwuagu, Eyerich, Farah, Ferwerda, Findlay, Fitzgerald, Gafa, Gafa, Gee, Gersuk, Gillessen, Glocker, Gollob, Goriely, Haines, Hall, Hamano, Hambleton, Happel, Hirahara, Hohl, Holscher, Hsieh, Huang, Huber, Humphreys, Hunter, Hunter, Huppler, Jones, Kagami, Kaposzta, Kisand, Kreindler, Kreymborg, Langrish, Lavigne, Lederer, LeibundGut-Landmann, Lev-Sagie, Lilly, Ling, Liu, Lucas, Ma, Manetti, Mathur, Mattner, Meiler, Mencacci, Milner, Miyazato, Molle, Montagnoli, Muller, Murdock, Murugaiyan, Nagai, Netea, Netea, Neufert, Niedbala, Oppmann, Orr, Owaki, Ozbek, Pacciani, Parham, Patin, Patin, Pedraza-Sanchez, Peters, Pflanz, Pflanz, Piccotti, Pietrella, Pirhonen, Podlaski, Pot, Puel, Puel, Ramaprakash, Reiner, Remoli, Rivera, Rivera, Robinson, Roilides, Romani, Romani, Saijo, Selinda J. Orr, Shimoda, Shimoda, Shimozato, Smeekens, Steele, Stritesky, Stumhofer, Stumhofer, Stumhofer, Sun, Takatori, Taylor, Thierfelder, Trinchieri, Tsumura, van de Veerdonk, Vignali, Villarino, Villarino, Wagener, Wang, Wei, Wells, Werner, Wirtz, Xu, Yamanaka, Yang, Yang, Yano, Yen, Yoshida, Yoshida, Yoshimoto, Yoshimura, Zahn, Zelante, Zelante, Zheng, Zhou, Zou   +170 more
core   +3 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong, Libin Shen, Daqing Ma, Jinchao Hou   +3 more
wiley   +1 more source