Results 101 to 110 of about 12,249 (194)

Dectin-1 agonist curdlan modulates innate immunity to Aspergillus fumigatus in human corneal epithelial cells [PDF]

International Journal of Ophthalmology, 2015
AIM: To explore the immunomodulatory effects of curdlan on innate immune responses against Aspergillus fumigatus (A. fumigatus) in cultured human corneal epithelial cells (HCECs), and whether C-type lectin receptor Dectin-1 mediates the immunomodulatory ...
Cheng-Cheng Zhu, Gui-Qiu Zhao, Jing Lin, Li-Ting Hu, Qiang Xu, Xu-Dong Peng, Xue Wang, Sheng Qiu   +7 more
doaj   +1 more source

Targeting antigens to dendritic cell receptors for vaccine development [PDF]

, 2013
Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system which play a key role in regulating immune responses. Depending on the method of antigen delivery, DCs stimulate immune responses or induce tolerance.
Apostolopoulos, Vasso, Stojanovska, Lily, Thalhammer, T, Tzakos, AG   +3 more
core   +2 more sources

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A, Lund, Sean, Walford, Hannah H   +2 more
core   +2 more sources

Biomolecular Corona Remodelling of Aspergillus fumigatus Extracellular Vesicles Shapes Immune Recognition and Macrophage Activation Programs

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Extracellular vesicles (EVs) released by Aspergillus fumigatus play key roles in fungal–host communication. Similar to synthetic nanoparticles, fungal EVs acquire a biomolecular corona composed of a tightly bound “hard” corona layer of fungal proteins and a dynamic “soft” layer of host‐derived molecules adsorbed upon contact with biological ...
Lucas Fabrício Bahia Nogueira, Bianca T. M. de Oliveira, Renan E. A. Piraine, Lucas de Faria Nogueira, Júlia L. Froldi, Henrique T. de Oliveira, Larwsk Hayann, Luiz H. S. Andrilli, Lucas A. Tavares, Pietro Ciancaglini, Fausto Almeida   +10 more
wiley   +1 more source

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair. [PDF]

, 2015
Helminth parasites can cause considerable damage when migrating through host tissues, thus making rapid tissue repair imperative to prevent bleeding and bacterial dissemination particularly during enteric infection.
Bürgi, J., Esser-von Bieren, J., Harris, N.L., Marsland, B.J., Sutherland, D.B., Urban, J.F., Verbeek, J.S., Volpe, B.   +7 more
core   +1 more source

Advances in Wine Yeast Autolysis: Biochemical and Molecular Mechanisms, and the Release of Organic Compounds in White and Sparkling Wines—An Updated Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos, Aniela Pinto Kempka   +1 more
wiley   +1 more source

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells [PDF]

The Journal of Immunology, 2009
Abstract House dust mites are a significant source of airborne allergen worldwide, but there is little understanding of how they so potently generate allergic inflammation. We found that extracts from the house dust mites Dermatophagoides farinae (Df) and Dermatophagoides pteronyssinus and from the mold Aspergillus fumigatus ...
Nora A, Barrett, Akiko, Maekawa, Opu M, Rahman, K Frank, Austen, Yoshihide, Kanaoka   +4 more
openaire   +2 more sources

A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins.

PLoS ONE, 2015
Fungal infections of the cornea can be sight-threatening and have a worse prognosis than other types of microbial corneal infections. Peptidoglycan recognition proteins (PGLYRP), which are expressed on the ocular surface, play an important role in the ...
Xia Hua, Xiaoyong Yuan, Zhijie Li, Terry G Coursey, Stephen C Pflugfelder, De-Quan Li   +5 more
doaj   +1 more source