Results 121 to 130 of about 22,245,271 (149)

Immune Camouflage in <i>Pythium insidiosum</i> Keratitis: A Hypothesis on Molecular Mimicry and Host Pattern Recognition Receptor Evasion. [PDF]

Clin Ophthalmol
Gurnani B, Kaur K.
europepmc   +1 more source

A novel whole cancer cell vaccine based on modified β-glucan elicits robust anti-tumor immunity. [PDF]

Theranostics
Huang J, Wang Y, Zhu J, Li L, Hu L, Zhou Y, Xiao B, Yu Y.   +7 more
europepmc   +1 more source

Dectin-1 is Pathogenic in Chronic Kidney Disease by Promoting Macrophage Infiltration and Transition to Myofibroblast. [PDF]

Int J Biol Sci
Shen L, Li J, Zhang A, Yan S, Sha W, Wang Y, Feng S, Wang C, Chen Z, Huang H, Li B, Ren P, Zhou S, Wu S, Wang Y, Shen Z, Rong S, Haller H, Jiang H, Chen J.   +19 more
europepmc   +1 more source

Molecular mechanisms of neutrophil regulatory network in anti-Candida infection. [PDF]

Front Immunol
Xu Y, Cheng R, Li W, Yu W, Chen C.
europepmc   +1 more source

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria
openaire  

Dectin-2 Deficiency Promotes Proinflammatory Cytokine Release From Macrophages and Impairs Insulin Secretion

Dectin-2 Deficiency Promotes Proinflammatory Cytokine Release From Macrophages and Impairs Insulin Secretion
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Dectin-2 Deficiency Promotes Pro-inflammatory Cytokine Release from Macrophages and Impairs Insulin Secretion.

Endocrinology, 2023
Pancreatic islet inflammation plays a crucial role in the etiology of type 2 diabetes (T2D). Macrophages residing in pancreatic islets have emerged as key players in islet inflammation.
Masamichi Fujita, T. Miyazawa, Keiichiro Uchida, Naohiro Uchida, Shojiro Haji, Seiichi Yano, Norifusa Iwahashi, Tomomi Hatayama, Shunsuke Katsuhara, Shintaro Nakamura, Yukina Takeichi, M. Yokomoto-Umakoshi, Yasutaka Miyachi, R. Sakamoto, Yoichirou Iwakura, Yoshihiro Ogawa   +15 more
semanticscholar   +3 more sources

Dectin-2 depletion alleviates osteoclast-induced bone loss in periodontitis via Syk/NOX2/ROS signaling.

Free Radical Biology and Medicine
Periodontitis is the sixth most common disease worldwide and is closely associated with various systemic diseases, impacting overall health. It is characterized by the over-differentiation and activity of osteoclasts, leading to increased bone resorption and subsequent bone loss. Current treatments for bone loss are not ideal, highlighting the need for
Wengwanyue Ye, Yilin Liao, Xiaoyu Liu, Yuting Wang, Ting Li, Yaoyu Zhao, Zhenru He, Jingqiu Chen, Mengjie Yin, Yue Sheng, Yangge Du, Yaoting Ji, Hong He   +12 more
semanticscholar   +3 more sources

Dectin-2 promotes house dust mite-skewed Th2 response through the activation of cDC2s.

Cellular Immunology, 2022
The role of Dectin-2 (gene symbol, Clec4n) in house dust mite (HDM) induced Th2 immune response and the exact mechanism remains controversial. In this study, we illustrated that, Clec4n-/- mice had decreased Th2 immune response following HDM challenge, which may ascribe to dramatically reduced type 2 conventional dendritic cells (cDC2s) in lung of ...
Y. Qu, Xiaotian Ma, Jiewen Deng, Y. Shang, Kun Shang, Xinyu Wang, Zhenhong Guo, Chong Bai   +7 more
semanticscholar   +3 more sources

392 Pattern recognition receptor Dectin-2 suppresses melanoma lung metastases

Journal of Investigative Dermatology
W. Pruessmann, A. Teegen, J. Pruessmann, C. Sadik   +3 more
semanticscholar   +2 more sources