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Effectiveness of deep brain stimulation in alleviating treatment-resistant schizophrenia: a systematic review [PDF]
European Journal of Translational MyologyThe complexity of schizophrenia, particularly in cases resistant to traditional pharmacological treatments, poses significant challenges for clinicians and researchers.
Mohsen Khosravi
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Deep brain stimulation for the treatment of Alzheimer’s disease: A safer and more effective strategy [PDF]
Neural Regeneration ResearchAlzheimer’s disease is the most common type of cognitive disorder, and there is an urgent need to develop more effective, targeted and safer therapies for patients with this condition.
Fan Zhang, Yao Meng, Wei Zhang
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Frontiers in Psychiatry, 2023 IntroductionObsessive-compulsive disorder (OCD) affects 2–3% of the global population, causing distress in many functioning levels. Standard treatments only lead to a partial recovery, and about 10% of the patients remain treatment-resistant.
Mohamed A. Abdelnaim +13 more
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Neural Plasticity, 2022 Temporal interference (TI) could stimulate deep motor cortex and induce movement without affecting the overlying cortex in previous mouse studies. However, there is still lack of evidence on potential TI effects in human studies.
Zhiqiang Zhu +7 more
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Brain Sciences, 2023 Background: Postural instability is one of the most restricting motor symptoms for patients with Parkinson’s disease (PD). While medication therapy only shows minor effects, it is still unclear whether medication in conjunction with deep brain ...
Tobias Heß +2 more
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Discovering Themes in Deep Brain Stimulation Research Using Explainable Artificial Intelligence
Biomedicines, 2023 Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a
Ben Allen
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Neural plasticity in human brain connectivity: the effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease. [PDF]
PLoS ONE, 2014 Positive clinical outcomes are now well established for deep brain stimulation, but little is known about the effects of long-term deep brain stimulation on brain structural and functional connectivity.
Tim J van Hartevelt +6 more
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Brain Sciences, 2023 Objective: To investigate whether impaired plantar cutaneous vibration perception contributes to axial motor symptoms in Parkinson’s disease (PD) and whether anti-parkinsonian medication and subthalamic nucleus deep brain stimulation (STN-DBS) show ...
Tobias Heß +3 more
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Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]
, 2015 Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul +9 more
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Interdisciplinary Neurosurgery, 2021 Background: The US Food and Drug Administration approved in 2015 the use of deep brain stimulation for Parkinson disease after “four years duration and with recent onset of motor complications”.
Paola Testini +4 more
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