Results 1 to 10 of about 317,816 (208)

Deep brain stimulation for treatment resistant obsessive compulsive disorder; an observational study with ten patients under real-life conditions

Frontiers in Psychiatry, 2023
IntroductionObsessive-compulsive disorder (OCD) affects 2–3% of the global population, causing distress in many functioning levels. Standard treatments only lead to a partial recovery, and about 10% of the patients remain treatment-resistant.
Mohamed A. Abdelnaim, Mohamed A. Abdelnaim, Verena Lang-Hambauer, Verena Lang-Hambauer, Tobias Hebel, Stefan Schoisswohl, Stefan Schoisswohl, Martin Schecklmann, Daniel Deuter, Daniel Deuter, Juergen Schlaier, Juergen Schlaier, Berthold Langguth, Berthold Langguth   +13 more
doaj   +1 more source

Anticipatory Postural Adjustments and Compensatory Postural Responses to Multidirectional Perturbations—Effects of Medication and Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease

Brain Sciences, 2023
Background: Postural instability is one of the most restricting motor symptoms for patients with Parkinson’s disease (PD). While medication therapy only shows minor effects, it is still unclear whether medication in conjunction with deep brain ...
Tobias Heß, Christian Oehlwein, Thomas L. Milani   +2 more
doaj   +1 more source

Temporal Interference (TI) Stimulation Boosts Functional Connectivity in Human Motor Cortex: A Comparison Study with Transcranial Direct Current Stimulation (tDCS)

Neural Plasticity, 2022
Temporal interference (TI) could stimulate deep motor cortex and induce movement without affecting the overlying cortex in previous mouse studies. However, there is still lack of evidence on potential TI effects in human studies.
Zhiqiang Zhu, Yiwu Xiong, Yun Chen, Yong Jiang, Zhenyu Qian, Jianqiang Lu, Yu Liu, Jie Zhuang   +7 more
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Discovering Themes in Deep Brain Stimulation Research Using Explainable Artificial Intelligence

Biomedicines, 2023
Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a
Ben Allen
doaj   +1 more source

Neural plasticity in human brain connectivity: the effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease. [PDF]

PLoS ONE, 2014
Positive clinical outcomes are now well established for deep brain stimulation, but little is known about the effects of long-term deep brain stimulation on brain structural and functional connectivity.
Tim J van Hartevelt, Joana Cabral, Gustavo Deco, Arne Møller, Alexander L Green, Tipu Z Aziz, Morten L Kringelbach   +6 more
doaj   +1 more source

Does Impaired Plantar Cutaneous Vibration Perception Contribute to Axial Motor Symptoms in Parkinson’s Disease? Effects of Medication and Subthalamic Nucleus Deep Brain Stimulation

Brain Sciences, 2023
Objective: To investigate whether impaired plantar cutaneous vibration perception contributes to axial motor symptoms in Parkinson’s disease (PD) and whether anti-parkinsonian medication and subthalamic nucleus deep brain stimulation (STN-DBS) show ...
Tobias Heß, Peter Themann, Christian Oehlwein, Thomas L. Milani   +3 more
doaj   +1 more source

Sex Disparities in the Self-Evaluation of Subthalamic Deep Brain Stimulation Effects on Mood and Personality in Parkinson's Disease Patients

Frontiers in Neurology, 2020
Changes in personality are one of the main concerns Parkinson's disease (PD) patients raise when facing the decision to undergo neurosurgery for deep brain stimulation (DBS) of the subthalamic nucleus (STN).
Amelie D. Dietrich, Johannes A. Koeppen, Carsten Buhmann, Monika Pötter-Nerger, Hans O. Pinnschmidt, Christian Oehlwein, Marita Oehlwein, Katrin Mittmann, Christian Gerloff, Andreas K. Engel, Manfred Westphal, Miriam Schaper, Wolfgang Hamel, Christian K. E. Moll, Alessandro Gulberti, Alessandro Gulberti   +15 more
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Neurosurgeons perspective on the shift towards earlier use of deep brain stimulation for Parkinson disease

Interdisciplinary Neurosurgery, 2021
Background: The US Food and Drug Administration approved in 2015 the use of deep brain stimulation for Parkinson disease after “four years duration and with recent onset of motor complications”.
Paola Testini, Harini Sarva, Jason Schwalb, Samantha Barkan, Laura Y. Cabrera   +4 more
doaj   +1 more source

Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]

, 2015
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul, Dauwe, Ine, Descamps, Benedicte, Keereman, Vincent, Raedt, Robrecht, Van Den Berge, Nathalie, Van Holen, Roel, van Mierlo, Pieter, Vanhove, Christian, Vonck, Kristl   +9 more
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Complications After Deep Brain Stimulation: A 21-Year Experience in 426 Patients

Frontiers in Aging Neuroscience, 2022
BackgroundDeep brain stimulation is an established treatment for movement disorders such as Parkinson’s disease, essential tremor, and dystonia. However, various complications that occur after deep brain stimulation are a major concern for patients and ...
In-Ho Jung, In-Ho Jung, Kyung Won Chang, So Hee Park, Won Seok Chang, Hyun Ho Jung, Jin Woo Chang   +6 more
doaj   +1 more source