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High-frequency deep brain stimulation (DBS) is an established therapy for Parkinson disease (PD), essential tremor, and primary dystonia, and is under investigation for several neuropsychiatric diseases. DBS for PD, in the subthalamic nucleus or globus pallidus interna (GPi), improves tremor, bradykinesia, and rigidity, emotional well-being and sleep ...
X L, Chen, Y Y, Xiong, G L, Xu, X F, Liu
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Deep brain stimulation (DBS) for the treatment of neurologic diseases has markedly increased in popularity over the past 15 years. This review primarily focuses on movement disorder applications and efficacy of DBS, but also briefly reviews other promising new and old uses of DBS.A multidisciplinary team consisting of a movement disorders neurologist ...
Drew S, Kern, Rajeev, Kumar
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IntroductionObsessive-compulsive disorder (OCD) affects 2–3% of the global population, causing distress in many functioning levels. Standard treatments only lead to a partial recovery, and about 10% of the patients remain treatment-resistant.
Mohamed A. Abdelnaim +13 more
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Temporal interference (TI) could stimulate deep motor cortex and induce movement without affecting the overlying cortex in previous mouse studies. However, there is still lack of evidence on potential TI effects in human studies.
Zhiqiang Zhu +7 more
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Deep brain stimulation (DBS) has provided remarkable benefits for people with a variety of neurologic conditions. Stimulation of the ventral intermediate nucleus of the thalamus can dramatically relieve tremor associated with essential tremor or Parkinson disease (PD).
Joel S, Perlmutter, Jonathan W, Mink
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Background: Postural instability is one of the most restricting motor symptoms for patients with Parkinson’s disease (PD). While medication therapy only shows minor effects, it is still unclear whether medication in conjunction with deep brain ...
Tobias Heß +2 more
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Deep Brain Stimulation in Schizophrenia [PDF]
Abstract Deep brain stimulation (DBS) has successfully advanced treatment options of putative therapy-resistant neuropsychiatric diseases. Building on this strong foundation more and more mental disorders in the stadium of therapy-resistance are considered as possible indications for DBS.
Kuhn, J. +7 more
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Neural plasticity in human brain connectivity: the effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease. [PDF]
Positive clinical outcomes are now well established for deep brain stimulation, but little is known about the effects of long-term deep brain stimulation on brain structural and functional connectivity.
Tim J van Hartevelt +6 more
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Discovering Themes in Deep Brain Stimulation Research Using Explainable Artificial Intelligence
Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a
Ben Allen
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