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Functional imaging of deep brain stimulation in dystonia: a review
Much remains to be learned about the mechanism of benefit of deep brain stimulation in movement disorders in general and dystonia specifically. A full accounting of the pathophysiology of dystonia additionally remains unclear.
Ian O. Bledsoe, Melanie A. Morrison
doaj +1 more source
Deep Brain Stimulation, Authenticity and Value [PDF]
In this paper, we engage in dialogue with Jonathan Pugh, Hannah Maslen, and Julian Savulescu about how to best interpret the potential impacts of deep brain stimulation on the self.
Nyholm, Sven, O’Neill, Elizabeth
core +2 more sources
Optogenetics and deep brain stimulation neurotechnologies [PDF]
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt+58 more
core +2 more sources
Deep brain stimulation for dystonia [PDF]
The few controlled studies that have been carried out have shown that bilateral internal globus pallidum stimulation is a safe and long-term effective treatment for hyperkinetic disorders. However, most recent published data on deep brain stimulation (DBS) for dystonia, applied to different targets and patients, are still mainly from uncontrolled case ...
Emmanuel Roze+4 more
openaire +5 more sources
End-to-end semantic segmentation of personalized deep brain structures for non-invasive brain stimulation [PDF]
Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an affordable clinical application that is applied through electrodes attached to the scalp.
arxiv +1 more source
Deep brain stimulation for dystonia [PDF]
Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory movement disorders, and has been approved by the United States Food and Drug Administration for treatment of dystonia. The success of DBS in the treatment of dystonia depends on our understanding of the anatomy and physiology of this disorder and close ...
Wei Hu, Matt Stead
openaire +3 more sources
Anxiety and depression exhibit high comorbidity and share the alteration of the amygdala–hippocampal–prefrontal network, playing different roles in the ventral and dorsal hippocampi.
Hanna Vila-Merkle+8 more
doaj +1 more source
Effects of electrical and optogenetic deep brain stimulation on synchronized oscillatory activity in Parkinsonian basal ganglia [PDF]
Conventional deep brain stimulation (DBS) of basal ganglia uses high-frequency regular electrical pulses to treat Parkinsonian motor symptoms and has a series of limitations. Relatively new and not yet clinically tested optogenetic stimulation is an effective experimental stimulation technique to affect pathological network dynamics.
arxiv +1 more source
Deep brain and cortical stimulation for epilepsy [PDF]
Background : Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in invasive intracranial neurostimulation as a treatment for these patients ...
Anderson+63 more
core +1 more source
Neurosurgery for Psychopaths? An Ethical Analysis [PDF]
Recent developments in neuroscience have inspired proposals to perform deep brain stimulation on psychopathic detainees. We contend that these proposals cannot meet important ethical requirements that hold for both medical research and therapy.
Hübner, Dietmar, White, Lucie
core +1 more source