Results 81 to 90 of about 317,965 (338)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection [PDF]

open access: yes, 2012
The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways\ud of the basal ganglia, is well positioned to efficiently mediate action selection.
Baltuch, G. H.   +5 more
core   +2 more sources

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Dopamine Dysregulation Syndrome and Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease

open access: yesNeurology Research International, 2011
Dopamine dysregulation syndrome is a complication of the dopaminergic treatment in Parkinson's disease that may be very disabling due to the negative impact that compulsive medication use may have on patients' social, psychological, and physical ...
Beatriz De la Casa-Fages   +1 more
doaj   +1 more source

Weight Change after Striatal/Capsule Deep Brain Stimulation Relates to Connectivity to the Bed Nucleus of the Stria Terminalis and Hypothalamus

open access: yesBrain Sciences, 2019
Weight changes are insufficiently understood adverse events of deep brain stimulation. In this context, exploring neural networks of weight control may inform novel treatment strategies for weight-related disorders.
Juan Carlos Baldermann   +7 more
doaj   +1 more source

Singing the Brain Electric [PDF]

open access: yes, 2008
Thesis (S.M. in Science Writing)--Massachusetts Institute of Technology, Dept. of Humanities, Graduate Program in Science Writing, 2008.Includes bibliographical references (p. [36]-[38]).Singing the Brain Electric Brain pacemakers, scientists have found,
Chua, Grace (Grace W. J.)
core  

Adverse Psychological Effects to Deep Brain Stimulation: Overturning the Question [PDF]

open access: yes, 2014
Our invited contribution is a response to Mecacci, G., and W. F. G. Haselager. 2014. Stimulating the self: The influence of conceptual frameworks on reactions to deep brain stimulation.
Moratti, Sofia, Patterson, Dennis
core   +1 more source

Deep Brain Stimulation for Epilepsy [PDF]

open access: yesNeuromodulation: Technology at the Neural Interface, 2009
Introduction. There is renewed interest in the use of electrical stimulation to control seizures in patients with medically refractory epilepsy. The evidence indicates that multiple nuclei are involved in the onset, spread, or termination of seizures. Establishing electrical stimulation parameters tailored to these nuclei that best control seizures is ...
Sean J. Nagel, Imad Najm
openaire   +3 more sources

The Diagnostic Value of Visual Evoked Potentials in Chronic Disorders of Consciousness

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In chronic disorders of consciousness (DOCs), the distinction between vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS) is as crucial as it is challenging. Evoked potentials (EPs) and event‐related potentials (ERPs) are helpful, but some limitations prevent their consistent use in the ...
Letizia Clementi   +14 more
wiley   +1 more source

Shared pathway-specific network mechanisms of dopamine and deep brain stimulation for the treatment of Parkinson’s disease

open access: yesNature Communications
Deep brain stimulation is a brain circuit intervention that can modulate distinct neural pathways for the alleviation of neurological symptoms in patients with brain disorders.
Thomas S. Binns   +19 more
doaj   +1 more source

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