Results 61 to 70 of about 5,284,179 (294)
Advanced Science, EarlyView.Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García +13 more
wiley +1 more source
Current clinical application of deep-brain stimulation for essential tremor
Neuropsychiatric Disease and Treatment, 2013 Amit Chopra, Bryan T Klassen, Matt Stead Department of Neurology, Mayo Clinic, Rochester, MN, USA Background: Deep-brain stimulation (DBS) is an established treatment for medically refractory essential tremor (ET).
Chopra A, Klassen BT, Stead M
doaj
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
Jurnal Neuroanestesi Indonesia, 2019 Deep brain stimulation (DBS) akhir-akhir ini sering digunakan untuk penyakit Parkinson dan kelainan pergerakan lainnya. DBS sendiri merupakan suatu stimulator yang ditanam pada nukleus dalam di otak dan disambungkan dengan pembangkit pulsasi yang ditanam
Dhania A Santosa +3 more
doaj +1 more source
Anthropology of Deep Brain Stimulation; the 30th Anniversary of
Movement Disorders Clinical Practice, 2023 Abstract Background The year 2023 marks the 30th anniversary of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson ’ s disease (PD).
Marwan Hariz +3 more
openaire +3 more sources
A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
Advanced Science, EarlyView.This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
Advanced Science, EarlyView.. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Penghui Chen +8 more
wiley +1 more source
Management of essential tremor deep brain stimulation-induced side effects
Frontiers in Human NeuroscienceDeep brain stimulation (DBS) is an effective surgical therapy for carefully selected patients with medication refractory essential tremor (ET). The most popular anatomical targets for ET DBS are the ventral intermedius nucleus (VIM) of the thalamus, the ...
Alfonso Enrique Martinez-Nunez +11 more
doaj +1 more source
Advanced Science, EarlyView.This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang +11 more
wiley +1 more source
Deep brain stimulation is an established treatment option for various neurological and psychiatric disorders. Throughout its journey as a confirmed long-term efficacious therapeutic option for movement disorders such as Parkinson’ s disease, essential ...
Değirmenci, Yıldız
core +1 more source