Results 71 to 80 of about 5,284,179 (294)

A Programmable High-Voltage Compliance Neural Stimulator for Deep Brain Stimulation in Vivo

, 2017
Deep brain stimulation (DBS) is one of the most effective therapies for movement and other disorders. The DBS neurosurgical procedure involves the implantation of a DBS device and a battery-operated neurotransmitter, which delivers electrical impulses to
Gong, Cihun-Siyong Alex;Lai, Hsin-Yi;Huang, Sy-Han;Lo, Yu-Chun;Lee, Nicole;Chen, Pin-Yuan;Tu, Po-Hsun;Yang, Chia-Yen;Lin, James Chang-Chieh;Chen, You-Yin
core   +1 more source

Low‐Intensity Focused Ultrasound Enables Temporal Modulation of Human Midbrain Organoid Differentiation

Advanced Science, EarlyView.
In this study, we demonstrate that low‐intensity ultrasound stimulation enables temporal modulation of midbrain organoid differentiation using a modular multi‐well stimulation platform. In particular, we show that ultrasound promotes the proliferation of dopaminergic progenitor cells.
Jinseong Jeong, Yehhyun Jo, Youngsun Lee, Eunyoung Jang, Yeonji Jeong, Won Do Heo, Jennifer H. Shin, Mi‐Ok Lee, Hyunjoo J. Lee   +8 more
wiley   +1 more source

Deep brain stimulation and tics

, 2014
When patients with Tourettes syndrome (TS) are refractory to behavioral, pharmacological and invasive nonsurgical treatment (botulinum toxin injection), a viable emerging option is deep brain stimulation (DBS)
Priori A.
core   +2 more sources

Progress on the application of deep brain stimulation in motor dysfunction after stroke

Chinese Journal of Contemporary Neurology and Neurosurgery
Stroke is one of the main causes of adult disability. Patients after stroke often suffer from motor dysfunction, which affects their quality of life and requires effective treatment methods.
WEI Xin-ming, FENG Ke-ke
doaj   +1 more source

Deep brain stimulation : effects on swallowing function in Parkinson's disease

, 2013
Objective: In patients with Parkinson’s disease (PD), deep brainstimulation of the subthalamic nucleus (STN DBS) is well recognizedin improving limb function, but the outcome on swallowing functionhas rarely been studied.
Sundstedt, Stina,, Kulneff, Linda,, Sundstedt, Stina, Linder, Jan,, van Doorn, Jan,, Nordh, Erik, Olofsson, Katarina,, van Doorn, Jan, Blomstedt, Patric, Kulneff, Linda, Nordh, Erik,, Olofsson, Katarina, Linder, Jan, Blomstedt, Patric,   +13 more
core   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

History of “Psychiatric” Deep Brain Stimulation: A Critical Appraisal

, 2012
Recent published statements on deep brain stimulation (DBS) claim that DBS was developed first for movement disorders and is now applied in psychiatry, that it was the behavioral and psychiatric side effects of DBS in the subthalamic nucleus (STN) in ...
Hariz, Marwan,, Marwan I. Hariz
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Deep brain stimulation lead migration in a child secondary to osteogenesis at the burr hole site

Interdisciplinary Neurosurgery, 2018
The frequency of deep brain stimulation (DBS) complications is low; however, lead migration is a common way DBS therapy can become ineffective. We present a case of a nine-year-old male with generalized dystonia who underwent bilateral GPi DBS lead ...
Cameron Brimley, M.D., Amir Kershenovich, M.D., M.H.A.   +1 more
doaj   +1 more source

Automatic Target and Trajectory Identification for Deep Brain Stimulation (DBS) Procedures [PDF]

, 2007
This paper presents an automatic surgical target and trajectory identification technique for planning deep brain stimulation (DBS) procedures. The probabilistic functional maps, constructed from population-based actual stimulating field information and intra-operative electrophysiological activities, were integrated into a neurosurgical visualization ...
Ting Guo, Andrew G. Parrent, Terry M. Peters   +2 more
openaire   +2 more sources