Results 131 to 140 of about 7,638,076 (261)

Circumscribed Meningeal Melanocytic Neoplasms: CNS WHO Grade, Molecular Profile, and Clinical Outcomes

open access: yesBrain Pathology, EarlyView.
In this study including 31 circumscribed meningeal melanocytic neoplasms (melanocytoma, intermediate‐grade melanocytic tumor [IMT], and melanoma), overall survival (OS) differed significantly among the groups, with melanoma showing significantly worse OS than melanocytoma and IMT showing intermediate OS between melanocytoma and melanoma.
Yi Zhu   +12 more
wiley   +1 more source

Machine learning prediction model for functional prognosis of acute ischemic stroke based on MRI radiomics of white matter hyperintensities

open access: yesBMC Medical Imaging
Objective The purpose of the current study is to explore the value of a nomogram that integrates clinical factors and MRI white matter hyperintensities (WMH) radiomics features in predicting the prognosis at 90 days for patients with acute ischemic ...
Yayuan Xia   +4 more
doaj   +1 more source

Chronic traumatic encephalopathy in a neuropathologically confirmed Creutzfeldt–Jakob disease cohort

open access: yesBrain Pathology, EarlyView.
Systematic neuropathological screening of 212 patients with Creutzfeldt–Jakob disease (55% women) identified chronic traumatic encephalopathy in three cases (1.4%), all men with a history of contact sports. These findings represent the first neuropathologically confirmed chronic traumatic encephalopathy cases reported in Spain.
Lluc Bertran   +13 more
wiley   +1 more source

Diabetes mellitus exacerbates changes in white matter hyperintensity shapes and volume: A longitudinal study

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION Although white matter hyperintensity (WMH) can progress over time, little is known about the underlying mechanisms. In addition, type 2 diabetes mellitus (T2DM) exacerbates the accumulation of WMH.
Shihao Xu   +6 more
doaj   +1 more source

Under pressure: the interplay of hypertension and white matter hyperintensities with cognition in chronic stroke aphasia

open access: yes
While converging research suggests that increased white matter hyperintensity load is associated with poorer cognition, and the presence of hypertension is associated with increased white matter hyperintensity load, the relationship among hypertension ...
Bonilha, Leonardo   +9 more
core   +1 more source

The characteristics of perivascular proinflammation in 4‐repeat tauopathies

open access: yesBrain Pathology, EarlyView.
The spatial distribution of perivascular proinflammation differs between PSP and CBD: PSP shows a predominance in basal ganglia (BG), whereas CBD demonstrates more widespread involvement of both BG and superior/middle frontal gyrus (S/M‐FG). PSP exhibits profound proinflammatory activation around venules while CBD affects a comparable magnitude around ...
Mu‐Hui Fu   +5 more
wiley   +1 more source

Thickening and enhancement of multiple cranial nerves in conjunction with cystic white matter lesions in early infantile Krabbe disease.

open access: yes, 2008
We present serial MR findings in a child ultimately diagnosed with the early infantile form of Krabbe disease. MR showed typical features of Krabbe disease including cerebellar and brainstem hyperintensity, periventricular and deep white matter ...
Schwartz, Erin S   +2 more
core   +1 more source

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study

open access: yesCardiovascular Diabetology
Background Sodium-glucose cotransporter 2 (SGLT2) and SGLT1 inhibitors may have additional beneficial metabolic effects on circulating metabolites beyond glucose regulation, which could contribute to a reduction in the burden of cerebral small vessel ...
Yanchen Lv, Xin Cheng, Qiang Dong
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu   +5 more
wiley   +1 more source

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