Results 151 to 160 of about 7,638,076 (261)

Correlations among lymphocyte count, white matter hyperintensity and brain atrophy in patients with ischemic stroke

open access: yesFrontiers in Aging Neuroscience
BackgroundWhite matter hyperintensity (WMH) and brain atrophy, as imaging marker of cerebral small-vessel diseases (CSVD), have a high prevalence and strong prognostic value in stroke. We aimed to explore the association between lymphocyte count, a maker
Chenchen Liu   +10 more
doaj   +1 more source

Brain MRI demonstrated white matter abnormality suggesting leukoencephalopathy in a patient homozygous for VPS11: c.2536T>G (p.C846G).

open access: yes, 2016
In patient B at nine months of age, thin corpus callosum (A), T2 diffuse hyperintensity in the peri-Rolandic white matter (B) and posterior occipital white matter region (C) were seen; FLAIR diffuse hyperintensity in the white matter region was also seen
Magalie Leduc (2633278)   +28 more
core   +1 more source

Investigating the Link Between Objective Sleep Metrics and Cerebral Small Vessel Disease in a Population‐Based Cohort

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Cerebral small vessel disease (CSVD), a disorder that affects the cerebral microvasculature, is commonly associated with aging and may contribute to dementia and stroke. Increasing evidence suggests a link between CSVD and sleep disturbances, but the association remains poorly understood.
Mareike Ludwig   +11 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

White Matter Hyperintensity-Adjusted Critical Infarct Thresholds to Predict a Favorable 90-Day Outcome

open access: yes
Background and Purpose - There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and ...
Patti, J   +3 more
core   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathology

open access: yesPeriodontology 2000, EarlyView.
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata   +3 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Chronic pruritus treated with alendronate in bilateral striopallidodentate calcinosis associated with an SLC20A2 gene mutation

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Adrien Boyard   +12 more
wiley   +1 more source

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