Results 141 to 150 of about 7,638,076 (261)

White matter hyperintensity burden in young patent foramen ovale patients and its correlation with migraine

Frontiers in Neurology
ObjectivePatent foramen ovale (PFO) may play an important role in the progression of white matter hyperintensity (WMH) through paradoxical embolism-induced chronic cerebral microcirculatory dysfunction.
Yuxuan Li, Yuxuan Li, Yangyingqiu Liu, Jinfeng Cao, Qun Shang, Wenjing Zheng, Wenjing Zheng, Jiaqi Li, Jiaqi Li, Xinying Shi, Xinying Shi, Jiaxiang Xin, Wei Zhao, Ye Meng, Bo Li, Xin Luo   +15 more
doaj   +1 more source

Early tocilizumab and outcomes in acute necrotizing encephalopathy

Developmental Medicine &Child Neurology, EarlyView.
Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han, Prithuja Poudyal, Vanessa Lee, Arushi Gahlot Saini, Shekeeb S Mohammad, Sekhar C Pillai, Gouri Rao Passi, Naveen Sankhyan, Ahmad Rithauddin Mohamed, Lokesh Lingappa, Hiroshi Sakuma, Russell C Dale, Ming Lim, Terrence Thomas, for The International ANE Study Group   +14 more
wiley   +1 more source

Automated rating of Fazekas scale in fluid-attenuated inversion recovery MRI for ischemic stroke or transient ischemic attack using machine learning

Scientific Reports
White matter hyperintensities (WMH) are commonly assessed using the Fazekas scale, a subjective visual grading system. Despite the emergence of deep learning models for automatic WMH grading, their application in stroke patients remains limited.
Eun-Tae Jeon, Seung Min Kim, Jin-Man Jung   +2 more
doaj   +1 more source

Deep Learning-Based Regional White Matter Hyperintensity Mapping as a Robust Biomarker for Alzheimer's Disease

CoRR
Accepted at SPIE - Medical Imaging Conference ...
Julia Machnio, Mads Nielsen, Mostafa Mehdipour-Ghazi   +2 more
openaire   +2 more sources

Early white matter involvement in an infant carrying a novel mutation in ACOX1

, 2016
We describe the clinical findings and MRI features observed in a child who presented a two-step disease course: he was hypotonic at birth and soon afterwards developed seizures, which were partially responsive to treatment; he subsequently showed ...
Pensato, V., Masson, Riccardo, Taroni, F., GUERRA, SILVIA, CERINI, ROBERTO, Gellera, C., SIMONATI, Alessandro   +6 more
core   +1 more source

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source

Impact of white matter hyperintensities on cognitive, motor and functional recovery in veterans following acute/subacute stroke: a prospective study

BMJ Neurology Open
Objective To evaluate how the presence and severity of white matter hyperintensities (WMHs) affect cognitive, motor and functional recovery in veterans during the acute to subacute phase post-stroke.Methods A total of 125 veterans were consecutively and ...
Chao Xu, Meheroz H Rabadi
doaj   +1 more source

Accelerating FLAIR imaging via deep learning reconstruction: potential for evaluating white matter hyperintensities

Japanese Journal of Radiology
Abstract Purpose To evaluate deep learning-reconstructed (DLR)–fluid-attenuated inversion recovery (FLAIR) images generated from undersampled data, compare them with fully sampled and rapidly acquired FLAIR images, and assess their potential for white matter hyperintensity evaluation.
Noriko Nishioka, Yukie Shimizu, Yukio Kaneko, Toru Shirai, Atsuro Suzuki, Tomoki Amemiya, Hisaaki Ochi, Yoshitaka Bito, Masahiro Takizawa, Yohei Ikebe, Hiroyuki Kameda, Taisuke Harada, Noriyuki Fujima, Kohsuke Kudo   +13 more
openaire   +2 more sources

Spaceflight-induced changes in white matter hyperintensity burden in astronauts

, 2017
Objective:To assess the effect of weightlessness and the respective roles of CSF and vascular fluid on changes in white matter hyperintensity (WMH) burden in astronauts.Methods:We analyzed prespaceflight and postspaceflight brain MRI scans from 17 ...
Alperin, Noam, Noam Alperin, Bagci, Ahmet M, Ahmet M. Bagci, Lee, Sang H, Sang H. Lee   +5 more
core   +1 more source

Recognizing Signs of Abusive Head Trauma

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Abusive head trauma (AHT) remains the leading cause of fatal traumatic brain injury in infants and young children. Diagnosis is frequently delayed or missed due to nonspecific clinical presentation and unreliable histories, making neuroimaging a critical component of the diagnostic process. Objective This review synthesises computed
Maísa Naomi Irie, Vinicius de Menezes Jarry, Matheus de Lima Ruffini, Adolfo Moraes de Souza, Mariana Dalaqua, Juliana Ávila Duarte, Andrea Fraga, Fabiano Reis   +7 more
wiley   +1 more source