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We report the case of a 15-year-old child with beta-thalassemia developing bilateral cataracts while receiving deferasirox, a newer iron chelator. She had been taking deferasirox for the past 10 years while receiving monthly blood transfusions.
Tushit Dhar +2 more
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Nefrotoxicidad por deferasirox [PDF]
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Medicina. Fecha de lectura: 12-12-2016Introducción: El deferasirox es un quelante de hierro oral utilizado como terapia de primera línea para la ...
Gallegos Villalobos, Angel
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Deferasirox as adjunctive therapy for mucormycosis.
Item does not contain fulltextMucormycosis can be devastating and, as yet, there are no ideal therapies available. Observations that iron chelation may be a useful adjunct to antifungal treatment encouraged Spellberg et al.
Donnelly, J.P., Lahav, M.
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Deferasirox-induced cytogenetic responses
PubMedID: 25733130Deferasirox (commercially formulated as Exjade®) is one of the effective iron chelators used in treatment of iron overload diseases.
Ila H.B., Arslan M.
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Dose-dependent change in LIC with deferasirox treatment ▪ Deferasirox; □ DFO
Copyright information:Taken from "Exjade® (deferasirox, ICL670) in the treatment of chronic iron overload associated with blood transfusion"Therapeutics and Clinical Risk Management 2007;3(2):291-299.Published online Jan 2007PMCID:PMC1936310.© 2007 Dove
Maria Domenica Cappellini (77687)
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Objectives: The aim of this study was to develop direct compressed and lyophilized fast disintegrating/dissolving tablets (FDTs) that enhanced disintegration and dissolution of deferasirox, a drug with poor solubility and bioavailability.
ÖNER, LEVENT +7 more
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Type-I hypersensitivity reaction secondary to deferasirox intake
Deferasirox is a new generation tridentate iron chelator. We report a ten-year old ß-thalassaemic boy, who had type-I hypersensitivity reaction due to deferasirox intake.
Ozmen, Serap +4 more
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Deferasirox therapy in children with fanconi aplastic anemia
Thirty-nine children with Fanconi aplastic anemia (FAA) have been followed up in our center between January 2008 and November 2010. Eight of these children (20%) with a transfusional iron overload had been undergoing deferasirox treatment during the ...
Azik, Fatih Mehmet +7 more
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Új deferasiroxszármazékok előállítása és vizsgálata
A diplomamunka célja deferasiroxból kiindulva ambidentát ligandumok, illetve ezek Co(III) és Ru(II) illetve kétfémes Co(III)/Ru(II) komplexeinek előállítása volt.
Vas, Péter Mihály
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Thalassemia is a heterogeneous grouping of genetic disorders resulting from decreased synthesis of the alpha or beta chains of hemoglobin. Anemia and iron overload are the main causes of morbidity and mortality due to thalassemia disease.
Zulkarnaen, Bambang Subakti +2 more
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