Results 81 to 90 of about 14,894 (236)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, Volume 15, Issue 8, Page 1246-1266, August 2025.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Iron-load increases the susceptibility of rat hearts to oxygen reperfusion damage. Protection by the antioxidant (+)-cyanidanol-3 and deferoxamine. [PDF]

, 1988
A M van der Kraaij, L. J. Mostert, H.G. van Eijk, J.F. Koster   +3 more
openalex   +1 more source

Topology in Biological Piezoelectric Materials

Advanced Materials, Volume 37, Issue 32, August 14, 2025.
This review summarizes the topological structures in biological piezoelectric materials, covering morphology evolution, spatial arrangement, and biomimetic strategies. These topologies modulate structure‐property relationships across multiple scales, enabling performance enhancement and multifunctional integration.
Chen Chen, Yanhu Zhang, Yi Zheng, Yi Zhang, Hongyi Liu, Jiang Wu, Liang Yang, Zhengbao Yang   +7 more
wiley   +1 more source

Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway

Frontiers in Immunology
IntroductionUlcerative colitis (UC) is a global gastrointestinal disease, which is mainly caused by both dysfunctional epithelial barrier and inflammation response.
Shubin Wang, Xiangjun Liu, Lu Xu, Jinyi Lang, Dengqun Liu, Dengqun Liu   +5 more
doaj   +1 more source

1655 IRON BALANCE IN A DEFEROXAMINE (D) TREATED HEMODIALYSIS PATIENT [PDF]

, 1985
Jerold Woodhead, Douglas N. Weismann, Pedro A de Alercon   +2 more
openalex   +1 more source

Integrative Single‐Cell Analysis Reveals Iron Overload‐Induced Senescence and Metabolic Reprogramming in Ovarian Endometriosis‐Associated Infertility

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Iron overload in ovarian endometriosis (OE) disrupts follicular function and contributes to infertility. This study maps iron‐induced cellular changes using single‐cell and spatial transcriptomics, revealing senescence phenotypes in OE patients and mouse models. Similar patterns are observed in aging ovaries, highlighting iron metabolism as a potential
Yangshuo Li, Wei Zhou, Jie Ding, Di Song, Wen Cheng, Jin Yu, Shuai Sun, Shanshan Mei, Xiaolan Liang, Qianqian Zhao, Yanping Kuang, Mingqing Li, Zhexin Ni, Chaoqin Yu, Yue Gao   +14 more
wiley   +1 more source

Mitochondria as Regulators of Nonapoptotic Cell Death in Cancer

MedComm, Volume 6, Issue 8, August 2025.
Mitochondrial fission and fusion are key processes in maintaining cellular health. Fission is driven by proteins like, Fis‐1, which recruits DRP‐1, to facilitate the division of mitochondria. Fusion, however, is mediated by mitofusion 1(MFN1), mitofusion 2(MFN2), and optic atrophy 1 (OPA1), which work together to merge mitochondria, allowing functional
Saloni Malla, Rabin Neupane, Saloni Sood, Noor Hussein, Mariam Abou‐Dahech, David Terrero, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +8 more
wiley   +1 more source

The Role of Ferroptosis in Women's Health and Diseases

MedComm, Volume 6, Issue 8, August 2025.
At present, there are many common women's diseases, such as preeclampsia (PE), ovarian cancer, and cervical cancer, endangering women's health. These diseases all over the world are characterized by high morbidity and mortality. In the past decade, ferroptosis, a unique pattern of programmed cell death primarily driven by iron‐dependent phospholipid ...
Qiang Xu, Chongying Zhu, Lin Li, Jiayong Li, Zihao An, Chao Tang   +5 more
wiley   +1 more source

Nanosponge for Iron Chelation and Efflux: A Ferroptosis‐Inhibiting Approach for Myocardial Infarction Therapy

Advanced Science
Myocardial infarction (MI), a consequence of coronary artery occlusion, triggers the degradation of ferritin, resulting in elevated levels of free iron in the heart and thereby inducing ferroptosis.
Qingbo Lv, Jun Lin, He Huang, Boxuan Ma, Wujiao Li, Jiawen Chen, Meihui Wang, Xiaoyu Wang, Guosheng Fu, Yun Xiao   +9 more
doaj   +1 more source

Mitochondrial Quality Control in Health and Disease

MedComm, Volume 6, Issue 8, August 2025.
Mitochondrial quality control (MQC) maintains cellular homeostasis by coordinating various processes such as fission, fusion, mitophagy, and mitochondria‐regulated cell death. Dysregulation of these mechanisms plays a key role in the development of many human diseases.
Lin Ye, Xinzhi Fu, Qi Li
wiley   +1 more source