Results 111 to 120 of about 6,869,765 (282)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
, 2015 Jiska M Balk,1 Guido RMM Haenen,1 Özgür M Koc,2 Ron Peters,3 Aalt Bast,1 Wim JF van der Vijgh,1 Ger H Koek,4 1Department of Toxicology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, 2Faculty of ...
Balk JM +6 more
core
Complexity of Constraint Satisfaction Problems over Finite Subsets of Natural Numbers [PDF]
, 2016 We study the computational complexity of constraint satisfaction problems that are based on integer expressions and algebraic circuits. On input of a finite set of variables and a finite set of constraints the question is whether the variables can be ...
Dose, Titus
core +1 more source
Evaluation of Candida bloodstream infection and antifungal utilization in a tertiary care hospital
BMC Infectious Diseases, 2018 Background Candida bloodstream infections carry a significant mortality risk, justifying the importance of adequate antifungal therapy. This study describes trends in antifungal consumption using the Defined Daily Dose (DDD) and Days of Therapy (DOT ...
Tatiana Aporta Marins +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacy
, 2010 Samuel L Washington III1, Alan W Shindel21School of Medicine, University of California at San Francisco, San Francisco, California, USA; 2Department of Urology, University of California at San Francisco, San Francisco, California, USAAbstract: Selective ...
Samuel L Washington III, Alan W Shindel
core
P-Optimal Proof Systems for Each NP-Set but no Complete Disjoint NP-Pairs Relative to an Oracle [PDF]
, 2019 Pudlák [P. Pudlák, 2017] lists several major conjectures from the field of proof complexity and asks for oracles that separate corresponding relativized conjectures.
Dose, Titus
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Journal of Dairy Science: Measurement of antimicrobial usage (AMU) on dairy farms is an important aspect of antimicrobial stewardship and has been performed using a variety of methods. The objectives of this observational study were to compare AMU estimated using data extracted
L.C.B. Juliano +4 more
doaj +1 more source
Estimating antibiotics consumption in a tertiary care hospital in Islamabad using a WHO's defined daily dose methodology. [PDF]
Antimicrob Resist Infect Control, 2023 Jabeen N, Ullah W, Khalid J, Samad Z.
europepmc +1 more source