Results 71 to 80 of about 1,369,784 (332)
Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome. [PDF]
, 2017 PurposeMetabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. Previously, we reported on progressive retinal degeneration in a spontaneous obese rat (WNIN/Ob) model.
Ayyagari, Radha +7 more
core
EMBO reports, 2005 Mitochondria are the main sites of biological energy generation in eukaryotes. These organelles are remnants of a bacterial endosymbiont that took up residence inside a host cell over 1,500 million years ago. Comparative genomics studies suggest that the mitochondrion is monophyletic in origin.
Mark, van der Giezen, Jorge, Tovar
openaire +2 more sources
Advances in Mathematics, 2023 Computing all critical points of a monomial on a very affine variety is a fundamental task in algebraic statistics, particle physics and other fields. The number of critical points is known as the maximum likelihood (ML) degree. When the variety is smooth, it coincides with the Euler characteristic.
Agostini, Daniele +6 more
openaire +2 more sources
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Ecotoxicology and Environmental SafetyThis study seeks to elucidate the molecular mechanisms by which polyethylene microplastics (PE-MPs) facilitate the progression of osteosarcoma through the modulation of the ITGA5/FAPα/LGMN protein complex.
Weilin Zhang +9 more
doaj +1 more source
Stationary measure of the driven two-dimensional q-Whittaker particle system on the torus
, 2015 We consider a q-deformed version of the uniform Gibbs measure on dimers on the periodized hexagonal lattice (equivalently, on interlacing particle configurations, if vertical dimers are seen as particles) and show that it is invariant under a certain ...
Corwin, Ivan, Toninelli, Fabio Lucio
core +3 more sources
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Journal of Biological EngineeringDisc degeneration often leads to a highly prevalent symptom known as low back pain. Healthy nucleus pulposus tissue exhibited a hypoxic environment devoid of blood vessels, while degenerated nucleus pulposus experienced hypoxic deterioration and the ...
Zhencong Li +9 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Journal of the American Medical Association, 1896 Figures 10, 11 and 12 illustrate the different stages of excessive and arrested development of the helix. For the purpose of giving a better description of the stigmata of the ear I have divided the ear into upper, middle and lower third. Figure 10 shows arrest of the helix as far up as the upper third, while the upper part is well developed. Figure 11
openaire +2 more sources