Results 21 to 30 of about 17,182 (211)
Scientific Reports, 2017 It has been noticed that neuraminidase (NA) stalk truncation has arisen from evolutionary adaptation of avian influenza A viruses (IAVs) from wild aquatic birds to domestic poultry.
Sehee Park +11 more
doaj +3 more sources
Correction: The N-glycan Glycoprotein Deglycosylation Complex (Gpd) from Capnocytophaga canimorsus Deglycosylates Human IgG [PDF]
PLOS Pathogens, 2015 Correction: The N-glycan Glycoprotein Deglycosylation Complex (Gpd) from Capnocytophaga canimorsus Deglycosylates Human ...
Francesco Renzi +5 more
openaire +5 more sources
Deglycosylation induces a novel distal conformation in the mannose receptor CD206 [PDF]
Scientific ReportsDeglycosylation can disrupt protein structure and dynamics in ways that compromise function. In this study, we examine the structural and functional consequences of N-glycan removal in the mannose receptor CD206, a multi-domain lectin involved in innate ...
Guadalupe Alvarez +4 more
doaj +2 more sources
The impact of Fc glycosylation on IgG susceptibility to hinge region chemical reduction: implications for the development of immunoassays [PDF]
Biochemistry and Biophysics ReportsAntibodies are glycoproteins, and Fc glycosylation plays a critical structural role in maintaining the proper folding of the CH2 domain. Deglycosylated IgGs exhibit an open CH2 domain conformation that structurally affects also the neighboring hinge ...
Vanessa Susini +5 more
doaj +2 more sources
Hybrid QM/MM study on the deglycosylation step of chitin hydrolysis catalysed by chitinase B from Serratia marcescens [PDF]
Maejo International Journal of Science and Technology, 2011 Chitinase B (ChiB) from Serratia marcescens is an exo-chitinase that degrades chitin chains from the non-reducing end by cleaving off a dimer or trimer sugar product.
Vannajan S. Lee
doaj +2 more sources
Simultaneous N-deglycosylation and digestion of complex samples on S-Traps enables efficient glycosite hypothesis generation [PDF]
, 2022 N-linked glycosylation is an important post-translational modification that is difficult to identify and quantify in traditional bottom-up proteomics experiments.
Chien-Wei, Wang +4 more
core +2 more sources
Cells, 2022 N-Glycanase 1 (NGLY1) is a cytosolic enzyme involved in removing N-linked glycans of misfolded N-glycoproteins and is considered to be a component of endoplasmic reticulum-associated degradation (ERAD).
Ashutosh Pandey +3 more
doaj +1 more source
Pharmacology Research & Perspectives, 2022 Anti‐proinflammatory cytokine therapies against interleukin (IL)‐6, tumor necrosis factor (TNF)‐α, and IL‐1 are major advancements in treating inflammatory diseases, especially rheumatoid arthritis.
Ikuno Uehara +7 more
doaj +1 more source
Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation
eLife, 2020 During endoplasmic reticulum-associated degradation (ERAD), the cytoplasmic enzyme N-glycanase 1 (NGLY1) is proposed to remove N-glycans from misfolded N-glycoproteins after their retrotranslocation from the ER to the cytosol. We previously reported that
Antonio Galeone +13 more
doaj +1 more source
Deglycosylation of PROM1 deletion mutants.
, 2022 Lysates from N2a cells were treated with deglycosylation mix II (NEB) and analyzed on western blot next to untreated controls. The blots were probed with mAB 13A4 and anti-Flag antibodies as indicated. (TIF)
Fatimah Matalkah (3497255) +3 more
core +1 more source