Results 111 to 120 of about 2,128,954 (339)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Nutritional characteristics of almond hulls treated with sodium hydroxide and urea or supplemented with polyethylene glycol as an alternative feed resource for ruminant nutrition in Mediterranean area: in vitro study

Cogent Food & Agriculture
This study aimed to evaluate the effect of chemical treatments of almond hulls (AH) issued from two mediterranean countries (Tunisia and Palestine) on chemical composition, gas production (GP), methane (CH4), and in vitro ruminal fermentation. Treatments
Halimeh Zoabi, Hajer Ammar, Soha Ghzayel, Bassam Abu Aziz, Ahmed Eid Kholif, Mario de Haro-Martí, Rym Ben Abdallah, Secundino Lopez, Mireille Chahine   +8 more
doaj   +1 more source

Degradabilidade ruminal das silagens de capim-napier produzidas com diferentes níveis de farelo de "batata diversa" Ruminal degradability of elephant grass produced with different levels of "discarded potato" meal

Ciência e Agrotecnologia, 2007
Com o propósito de minimizar os custos com a alimentação, tem-se buscado a utilização dos resíduos viáveis à nutrição animal. "Batata diversa" é o nome atribuído ao tubérculo impróprio para o consumo humano, pois não alcança padrões de comercialização ...
Valério Mendes Rezende, Paulo César de Aguiar Paiva, Adauto Ferreira Barcelos, Júlio César Teixeira, Denismar Alves Nogueira   +4 more
doaj   +1 more source

EFFECT OF SOLID STATE FERMENTATION ON NUTRITIONAL CONTENT AND EVALUATION OF DEGRADABILITY IN CACTUS PEAR

, 2015
* ABSTRACT - The process of protein enrichment of cactus pear (Nopalea cochenillifera (L.) Salm Dyck) by solid state fermentation with the use of Aspergillus niger and Rhyzopus sp.
Tamires Carvalho Santos, Gleiza Alves Diniz, A. R. Brito, A. Pires, Marcelo Franco   +4 more
semanticscholar   +1 more source

Prediction of rumen degradability parameters of a wide range of forages and non-forages by NIRS.

Animal, 2015
Kinetics of nutrient degradation in the rumen is an important component of feed evaluation systems for ruminants. The in situ technique is commonly used to obtain such dynamic parameters, but it requires cannulated animals and incubations last several ...
A. Foskolos, S. Calsamiglia, M. Chrenková, M. Weisbjerg, Elena Albanell   +4 more
semanticscholar   +1 more source

Thermal analysis of amorphous oxide thin-film transistor degraded by combination of joule heating and hot carrier effect [PDF]

, 2013
Satoshi Urakawa, Shigekazu Tomai, Yoshihiro Ueoka, Haruka Yamazaki, Masashi Kasami, Koki Yano, Dapeng Wang, Mamoru Furuta, Masahiro Horita, Yasuaki Ishikawa, Yukiharu Uraoka   +10 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR Degradation [PDF]

, 2018
Ji Hye Kim, Boas Nam, Yun Jung Choi, Seon Ye Kim, Jungeun Lee, Ki Jung Sung, Woo Sung Kim, Chang‐Min Choi, Eun‐Ju Chang, Jae Soo Koh, Joon Seon Song, Shinkyo Yoon, Jae Cheol Lee, Jin Kyung Rho, Jaekyoung Son   +14 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source