Results 91 to 100 of about 38,202 (297)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Predicting Drug Release From Degradable Hydrogels Using Fluorescence Correlation Spectroscopy and Mathematical Modeling

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Predicting release from degradable hydrogels is challenging but highly valuable in a multitude of applications such as drug delivery and tissue engineering.
Saahil Sheth   +4 more
doaj   +1 more source

Nanoporosity improved water absorption, in vitro degradability, mineralization, osteoblast responses and drug release of poly(butylene succinate)-based composite scaffolds containing nanoporous magnesium silicate compared with magnesium silicate

open access: yes, 2017
Zhaoying Wu,1 Quan Li,2 Yongkang Pan,1 Yuan Yao,1 Songchao Tang,1 Jiacan Su,2 Jung-Woog Shin,3 Jie Wei,1 Jun Zhao4,5 1Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, 2Department of ...
Wu Z   +8 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Nanoporous diopside modulates biocompatibility, degradability and osteogenesis of bioactive scaffolds of gliadin-based composites for new bone formation

open access: yes, 2018
Zhaoyu Ba,1,* Zhaoxiong Chen,1,* Yufeng Huang,1,* Du Feng,2 Qinghui Zhao,3 Jianguang Zhu,1 Desheng Wu1 1Department of Spinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; 2Key Laboratory of Protein Modification ...
Huang Y   +6 more
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Nitrogen degradability and intestinal digestibility of rumen undegraded protein in rapeseed, rapeseed meal and extracted rapeseed meal

open access: yesCzech Journal of Animal Science, 2007
In this study, nutritive values of rapeseed (R), rapeseed meal-expeller A (RM-A), rapeseed meal-expeller B (RM-B) and extracted rapeseed meal (ERM) were compared.
P. Homolka, J. Harazim, J. Třináctý
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Biochar for Horticultural Rooting Media Improvement: Evaluation of Biochar from Gasification and Slow Pyrolysis

open access: yesAgronomy, 2017
Peat is used as rooting medium in greenhouse horticulture. Biochar is a sustainable alternative for the use of peat, which will reduce peat derived carbon dioxide emissions.
Chris Blok   +7 more
doaj   +1 more source

Tuning by degradation [PDF]

open access: yesNature Methods, 2019
A library of degrons allows tuning of half-life and expression levels of proteins in genetic circuits.
openaire   +2 more sources

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