Results 111 to 120 of about 33,224 (307)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Degradation of MRCVS

open access: yesVeterinary Record, 2019
IN the distant past when I graduated and hence was accepted as MRCVS, I immediately went into practice. This was quite legal and appropriate. I later moved out of conventional practice but I continued doing jobs for which MRCVS was obligatory; and I was employed to be consulted on veterinary issues.
openaire   +2 more sources

Degradability of plastics. Standard methods developed in Italy

open access: yes, 2000
Degradability of plastics.
Francesco Degli-Innocenti (17226865)   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Evaluation of degradability of biodegradable polyethylene (PE)

open access: yes, 2003
Evaluation of degradability of biodegradable polyethylene (PE)
Jakubowicz, Ignacy,
core  

Metabolism of soluble proteins by rumen microorganisms and the influence of condensed tannins on nitrogen solubility and degradation [PDF]

open access: yes, 2004
The amino acid requirements of ruminants are met by two sources; microbes leaving the rumen and dietary protein escaping fermentation in the rumen. Much ruminant research has therefore focused on improving amino acid supply to the duodenum by increasing ...
Hedqvist, Helena
core  

Estudo das propriedades mecânicas e elétricas de fibras de curauá modificada com polianilina Study on mechanical and electrical properties of curaua fibers modified with polianiline

open access: yesPolímeros, 2010
Fibras naturais têm sido empregadas em diversos compósitos, principalmente na indústria automobilística. Dentre as diversas fibras naturais, a fibra de curauá é atraente por apresentar elevada propriedade mecânica associada a baixos valores de densidade.
Fernando G. de S. Junior   +3 more
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Sonication to Improve Date Palm Seed Degradability in The Rumen

open access: yes, 2019
The main objective of this research was to evaluate the effects of chemical treatment and ultrasound processing (sonication) on the fiber composition and rumen degradability of date palm seeds (DPS). For this purpose, five trials were conducted.
Aboragah, Ahmad A
core  

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