Results 51 to 60 of about 579,743 (356)

Stochastic Modeling of Expression Kinetics Identifies Messenger Half-Lives and Reveals Sequential Waves of Co-ordinated Transcription and Decay [PDF]

, 2012
The transcriptome in a cell is finely regulated by a large number of molecular mechanisms able to control the balance between mRNA production and degradation. Recent experimental findings have evidenced that fine and specific regulation of degradation is
Cacace, Filippo, Cusimano, Valerio, FARINA, Lorenzo, Germani, Alfredo, PACI, PAOLA   +4 more
core   +3 more sources

Styrene photocatalytic degradation reaction kinetics [PDF]

Journal of the Brazilian Chemical Society, 2011
The aqueous styrene photocatalytic degradation reaction was evaluated using TiO2 P-25 (Degussa) as a catalyst. These experiments were accomplished in a batch slurry reactor with temperature control and a UV lamp. The effects of the initial styrene concentration, the catalyst concentration, the hydrogen peroxide addition and the initial pH of the ...
Taffarel, Silvio R., Lansarin, Marla A., Moro, Celso C.   +2 more
openaire   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Genetic and Biochemical Characterization of 2-Chloro-5-Nitrophenol Degradation in a Newly Isolated Bacterium, Cupriavidus sp. Strain CNP-8

Frontiers in Microbiology, 2017
Compound 2-chloro-5-nitrophenol (2C5NP) is a typical chlorinated nitroaromatic pollutant. To date, the bacteria with the ability to degrade 2C5NP are rare, and the molecular mechanism of 2C5NP degradation remains unknown.
Jun Min, Weiwei Chen, Jinpei Wang, Xiaoke Hu   +3 more
doaj   +1 more source

Photopolymerized thermosensitive poly(HPMAlactate)-PEG-based hydrogels : effect of network design on mechanical properties, degradation, and release behavior [PDF]

, 2010
Photopolymerized thermosensitive A-B-A triblock copolymer hydrogels composed of poly(N-(2-hydroxypropyl)-methacrylamide lactate) A-blocks, partly derivatizal with methacrylate groups to different extents (10, 20, and 30%) and hydrophilic poly(ethylene ...
Braeckmans, Kevin, Censi, Roberta, De Smedt, Stefaan, Deschout, Hendrik, di Martino, Piera, Hennink, Wim E, van Nostrum, Cornelus F, Vermonden, Tina   +7 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Degradation transformations in topologically disordered solids: 4. Features of exponential kinetics

Технологія та конструювання в електронній апаратурі, 2005
The manifestations of exponential degradation kinetics in topologically disordered materials are analyzed. Degradation transformations are determined by a single prevailing activation energy value, regardless of the structural dispersity of the system ...
V. A. Balitskaya, I. M. Brunets, М. M. Vakiv, G. I. Klim, O. I. Shpotyuk   +4 more
doaj  

Passage and degradation kinetics of solid particles from agricultural residues

Semina: Ciências Agrárias
The use of waste generated in the agroindustry can result in increased production at a relatively low cost compared to traditional ingredients, especially for producers with easy access to this waste.
Marco Aurélio Teixeira Andrade, Bruna Cardoso Braga, Severino Delmar Junqueira Villela, Raphael dos Santos Gomes, Maria Eduarda Lara Resende, Guilherme Campos Leitão, Fernando de Paula Leonel   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source