Results 11 to 20 of about 23,764 (211)

Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance. [PDF]

, 2006
Phthalate diesters have been shown to be developmental and reproductive toxicants in animal studies. A recent epidemiologic study showed certain phthalates to be significantly associated with reduced anogenital distance in human male infants, the first ...
Axelrad, Daniel, Calafat, Antonia, Marsee, Kevin, Swan, Shanna, Woodruff, Tracey   +4 more
core   +2 more sources

The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS

Antioxidants, 2021
The characteristics of phthalates had been thought to be similar to endocrine disruptors, which increases cancer risk. The role of phthalates in acquired drug resistance remains unclear.
Mahendra Jadhao, E. Tsai, Ho-Chun Yang, Yih-Fung Chen, Shih-Shin Liang, Tsu-Nai Wang, Y. Teng, Hurng-Wern Huang, Li-Fang Wang, Chien-Chih Chiu   +9 more
semanticscholar   +1 more source

Ecological Risk Assessment of Phthalate Esters (DBP and DEHP) in Surface Water of China

Frontiers in Environmental Science, 2021
As a new type of pollutant, phthalate esters (PAEs) are common organic compounds in industrial production and daily life, which are widely detected in surface water environment.
Fuhong Sun, Y. Tao, Di Shi, Jiwei Yang, Huixian Li, Yuan Wei, Hailei Su   +6 more
semanticscholar   +1 more source

Teratogenicity/Fetotoxicity of DEHP in Mice [PDF]

Environmental Health Perspectives, 1982
The embryonic/fetotoxic effects of DEHP on pregnant mice (ddY-Slc female x CBA male) were studied. DEHP was administered orally in dosages of 0.05 ml/kg to 30.0 mg/kg on day 6, 7, 8, 9 or 10 of gestation. A single administration of DEHP over 0.1 ml/kg (1/300 of LD50) on day 7 of gestation decreased the numbers and the body weight of living fetuses ...
I, Tomita, Y, Nakamura, Y, Yagi, K, Tutikawa   +3 more
openaire   +2 more sources

A method validation for simultaneous determination of phthalates and bisphenol A released from plastic water containers [PDF]

, 2019
Phthalates (or phthalate esters, PAEs) and bisphenol A (BPA) are widely used in various industries, particularly in the fields of cosmetics and packaging, and they increase the malleability and workability of materials.
Avino, P., Bhattacharya, B., Notardonato, I., Protano, C., Vitali, M.   +4 more
core   +1 more source

Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features [PDF]

, 2015
Internal levels of selected endocrine disruptors (EDs) (i.e., perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), di-2-ethylhexyl-phthalate (DEHP), mono-(2-ethylhexyl)-phthalate (MEHP), and bisphenol A (BPA)) were analyzed in blood/serum of ...
Bergamasco B, Bordi G, Busani L, Caserta D, Ciardo F, Focardi S, Guerranti C, La Rocca C, Mancini FR, Mantovani A, Marci R, Moscarini M, Perra G, Stecca L, Tait S   +14 more
core   +2 more sources

Update of the risk assessment of di‐butylphthalate (DBP), butyl‐benzyl‐phthalate (BBP), bis(2‐ethylhexyl)phthalate (DEHP), di‐isononylphthalate (DINP) and di‐isodecylphthalate (DIDP) for use in food contact materials

EFSA journal. European Food Safety Authority, 2019
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP Panel) was asked by the European Commission to update its 2005 risk assessments of di‐butylphthalate (DBP), butyl‐benzyl‐phthalate (BBP), bis(2‐ethylhexyl)phthalate (DEHP), di ...
V. Silano, José Manuel Barat Baviera, C. Bolognesi, A. Chesson, P. Cocconcelli, Riccardo Crebelli, D. Gott, K. Grob, E. Lampi, A. Mortensen, G. Rivière, I. Steffensen, C. Tlustos, Henk van Loveren, L. Vernis, Holger Zorn, J. Cravedi, C. Fortes, Maria de Fátima Tavares Poças, I. Waalkens-Berendsen, D. Wölfle, D. Arcella, C. Cascio, A. Castoldi, Katharina Volk, L. Castle   +25 more
semanticscholar   +1 more source

Dose-Dependent Effects of Di-(2-Ethylhexyl) Phthalate (DEHP) in Mussel Mytilus galloprovincialis

Frontiers in Marine Science, 2021
Phthalic acid esters (PAEs) are environmental organic pollutants that are ubiquitous in the ocean, and di-(2-ethylhexyl) phthalate (DEHP) is the most widely used PAE. The environmental concentration of DEHP was reported to be up to 42.52 μg/L in seawater
Hai’e Xu, Wanshuang Cao, Hongliang Sun, Shougang Zhang, Pan Li, Surong Jiang, Caiyun Zhong   +6 more
semanticscholar   +1 more source

Synergistic disruption of external male sex organ development by a mixture of four antiandrogens [PDF]

, 2009
Reproduced with permission from Environmental Health Perspectives.Background: By disrupting the action of androgens during gestation, certain chemicals present in food, consumer products, and the environment can induce irreversible demasculinization and ...
Andreas Kortenkamp, Anne Marie Vinggaard, COT, Hib J, Majken Dalgaard, Marta Axelstad, Martin Scholze, National Research Council, Sofie Christiansen, U.S. EPA, U.S. EPA, U.S. EPA (Environmental Protection Agency), Ulla Hass, VKM (Vitenskapskomiteen for Mattrygghet), Vonesh E   +14 more
core   +3 more sources

DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption

Endocrinology and Metabolism, 2021
Background Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland.
Min Joo Kim, H. Kim, Young Shin Song, O. Kim, Kyungho Choi, Sujin Kim, Byung-Chul Oh, Y. J. Park   +7 more
semanticscholar   +1 more source