Results 11 to 20 of about 39,361 (246)

Dehydroepiandrosterone and Its Metabolite 5-Androstenediol: New Therapeutic Targets and Possibilities for Clinical Application [PDF]

Pharmaceuticals
Dehydroepiandrosterone and its sulfate are the most abundant steroids in humans. The metabolism of dehydroepiandrosterone can differ significantly depending on the organ or tissue and the subtype of steroid receptors expressed in it.
Tatiana A. Fedotcheva, Maria E. Uspenskaya, Darya N. Ulchenko, Nikolay L. Shimanovsky   +3 more
doaj   +2 more sources

Hypoxia and dehydroepiandrosterone in old age: a mouse survival study [PDF]

Respiratory Research, 2006
Background Survival remains an issue in pulmonary hypertension, a chronic disorder that often affects aged human adults. In young adult mice and rats, chronic 50% hypoxia (11% FIO2 or 0.5 atm) induces pulmonary hypertension without threatening life.
Quillard Janine, Baulieu Etienne-Emile, Debonneuil Edouard H   +2 more
doaj   +4 more sources

Mathematical analysis of work aorto-mesenteric "forceps"

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2020
It is generally accepted that the diagnostic criteria for hemodynamically significant compression of the left renal vein are the anteroposterior size of the renal vein determined by ultrasound examination in the narrowed area of 1.5–2.5 mm or less ...
A. G. Tonyan, R. Sh. Muslimov, O. I. Zhdamarova   +2 more
doaj   +1 more source

Dehydroepiandrosterone and Its CYP7B1 Metabolite 7α-Hydroxydehydroepiandrosterone Regulates 11β-Hydroxysteroid Dehydrogenase 1 Directions in Rat Leydig Cells

Frontiers in Endocrinology, 2020
Background: The purpose of this study was to investigate cytochrome P450-7B1 (CYP7B1) in the human and rat testes to regulate 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) activity.
Qiqi Zhu, Yaoyao Dong, Xiaoheng Li, Chaobo Ni, Tongliang Huang, Jianliang Sun, Ren-Shan Ge   +6 more
doaj   +1 more source

Metabolic Analysis of Schizochytrium Mutants With High DHA Content Achieved With ARTP Mutagenesis Combined With Iodoacetic Acid and Dehydroepiandrosterone Screening

Frontiers in Bioengineering and Biotechnology, 2021
High DHA production cost caused by low DHA titer and productivity of the current Schizochytrium strains is a bottleneck for its application in competition with traditional fish-oil based approach.
Lei Zeng, Lei Zeng, Lei Zeng, Yanqi Bi, Yanqi Bi, Yanqi Bi, Pengfei Guo, Pengfei Guo, Pengfei Guo, Yali Bi, Yali Bi, Yali Bi, Tiantian Wang, Tiantian Wang, Tiantian Wang, Liang Dong, Liang Dong, Liang Dong, Fangzhong Wang, Fangzhong Wang, Lei Chen, Lei Chen, Lei Chen, Weiwen Zhang, Weiwen Zhang, Weiwen Zhang, Weiwen Zhang   +26 more
doaj   +1 more source

Feasibility of a liver transcriptomics approach to assess bovine treatment with the prohormone dehydroepiandrosterone (DHEA) [PDF]

, 2010
Background Within the European Union the use of growth promoting agents in animal production is prohibited. Illegal use of natural prohormones like dehydroepiandrosterone (DHEA) is hard to prove since prohormones are strongly metabolized in vivo.
Maria J Groot, Nielen Michel WF, Hende, J., van, Hendriksen, P.J.M., Rijk Jeroen CW, Peijnenburg Ad ACM, Nielen, M.W.F., Van Hende Johan M, Michel WF Nielen, Johan M Van Hende, Groot Maria J, Rijk, J.C.W., Hendriksen Peter JM, Ad ACM Peijnenburg, Peijnenburg, A.A.C.M., Peter JM Hendriksen, Groot, M.J., van Hende, J., Jeroen CW Rijk   +18 more
core   +1 more source

Dehydroepiandrosterone augments sensitivity to gamma-ray irradiation in human H4 neuroglioma cells through down-regulation of Akt signaling. [PDF]

, 2008
Dehydroepiandrosterone (DHEA) modulates sensitivity to radiation-induced injury in human neuroglioma cells (H4) through effects on Akt signalling by glutathione (GSH)-dependent redox regulation.
Akishita, Masahiro, Nagata, Izumi, Kondo, Takahito, Urata, Yoshishige, Kawakatsu, Miho, Matsuo, Takayuki, Kageyama, Kan, Matsuse, Michiko, Ikezaki, Midori, Hirao, Tomohito   +9 more
core   +1 more source

Effects of dehydroepiandrosterone supplementation on women with poor ovarian response: A preliminary report and review

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To investigate the effect of dehydroepiandrosterone (DHEA) supplementation on women with poor ovarian response (POR). Materials and methods: Women with POR treated with flexible daily gonadotropin-releasing hormone antagonist in vitro ...
Kuan-Hao Tsui, Li-Te Lin, Renin Chang, Ben-Shian Huang, Jiin-Tsuey Cheng, Peng-Hui Wang   +5 more
doaj   +1 more source

RETRACTED: Abnormal Plasma Levels of Steroids and Their Ratios in Patients With Prurigo Nodularis: A Pilot Study

Frontiers in Physiology, 2022
Background: It has been suggested that cortisol levels are abnormal in chronic urticaria and atopic dermatitis, but other steroids, such as dehydroepiandrosterone (DHEA) and testosterone, are still unknown, and whether these hormones affect the ...
Liuxi Chu, Liuxi Chu, Liuxi Chu, Xin Shu, Yan Wu, Yan Wu, Yan Wu, Haoran Yang, Haoran Yang, Haoran Yang, Qin Lu, Qin Lu, Huihua Deng, Huihua Deng, Huihua Deng   +14 more
doaj   +1 more source

The Utilization of Dehydroepiandrosterone as a Sexual Hormone Precursor in Premenopausal and Postmenopausal Women: An Overview

Pharmaceuticals, 2021
Dehydroepiandrosterone (DHEA), and its metabolite, dehydroepiandrosterone sulfate ester (DHEAS), are the most abundant circulating steroid hormones, and are synthesized in the zona reticularis of the adrenal cortex, in the gonads, and in the brain.
Justine Tang, Li-Ru Chen, Kuo-Hu Chen
doaj   +1 more source