Results 21 to 30 of about 39,361 (246)

Dehydroepiandrosterone supplementation in healthy men with an age-related decline of dehydroepiandrosterone secretion [PDF]

, 2001
Serum dehydroepiandrosterone declines with age. Whether this represents a harmful deficiency or an age-related adaptation is not known. Dehydroepiandrosterone replacement in adrenal insufficiency, a state of pathological loss of dehydroepiandrosterone ...
Ernst, M, Reincke, M, van Vlijmen, J C, Oettel, M, Fassnacht, M, Schulte, H M, Arlt, W, Callies, F, Seibel, M J, Huebler, D, Strasburger, C J, Allolio, B, Koehler, I   +12 more
core   +1 more source

DHEA Supplementation Confers No Additional Benefit to that of Growth Hormone on Pregnancy and Live Birth Rates in IVF Patients Categorized as Poor Prognosis

Frontiers in Endocrinology, 2018
BackgroundIn vitro fertilization (IVF) patients receive various adjuvant therapies to enhance success rates, but the true benefit is actively debated. Growth hormone (GH) and dehydroepiandrosterone (DHEA) supplementation were assessed in women undergoing
Kevin N. Keane, Kevin N. Keane, Peter M. Hinchliffe, Philip K. Rowlands, Gayatri Borude, Shanti Srinivasan, Satvinder S. Dhaliwal, John L. Yovich, John L. Yovich   +8 more
doaj   +1 more source

Effects of Wash Protocol and Contamination Level on Concentrations of Cortisol and Dehydroepiandrosterone (DHEA) in Swine Hair

Animals, 2021
The effect of washing procedure and contamination level on the concentrations of cortisol and dehydroepiandrosterone (DHEA) in swine hair was explored over two studies.
Darian S. Pollock, David M. Janz, Diego Moya, Yolande M. Seddon   +3 more
doaj   +1 more source

Identification of steroid sulfate transport processes in the human mammary gland [PDF]

, 2003
Circulating hormones and local biotransformation of steroid precursors are both sources of estrogen in human mammary tissue. Estrone-3-sulfate (E(1)S) is an important estrogenic form in premenopausal women, and dehydroepiandrosterone sulfate (DHEAS ...
Pizzagalli, F., Meier, P. J., Varga, Z., Huber, R. D., Folkers, G., St-Pierre, M. V.   +5 more
core   +1 more source

Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus

Journal of Diabetes Investigation, 2023
Aims This cross‐sectional study assessed the association of serum dehydroepiandrosterone levels with the risk of diabetic retinopathy in patients with type 2 diabetes mellitus in China.
Xinxin Zhang, Yadi Huang, Ning Xu, Wenli Feng, Jingting Qiao, Ming Liu   +5 more
doaj   +1 more source

Injurious Effect of Cisplatin on the Function of Hypothalamus-pituitary-adrenal/gonadal Axis in Mice and the Intervention Effect of Dehydroepiandrosterone

Shiyan dongwu yu bijiao yixue, 2023
Objective To study the pathway of cis-dichlorodiamineplatinum (DDP) inhibiting the synthesis of steroid hormones in mice, and to observe the intervention effect of dehydroepiandrosterone (DHEA).
PAN Zhiqiang, NONG Zixin, XIE Haina, PENG Peike   +3 more
doaj   +1 more source

An Improved Dehydroepiandrosterone-Induced Rat Model of Polycystic Ovary Syndrome (PCOS): Post-pubertal Improve PCOS's Features

Frontiers in Endocrinology, 2018
Complete animal models investigating the pathogenesis and treatment of polycystic ovarian syndrome (PCOS) are not completely established. Although dehydroepiandrosterone (DHEA)-induced pre-pubertal rat model for PCOS has been widely used, the model ...
Eun-Jeong Kim, Eun-Jeong Kim, Minhee Jang, Jong Hee Choi, Jong Hee Choi, Kyoung Sun Park, Ik-Hyun Cho, Ik-Hyun Cho, Ik-Hyun Cho   +8 more
doaj   +1 more source

Metabolism of dehydroepiandrosterone and dehydroepiandrosterone sulfate in tissue extracts of rabbit ovaries [PDF]

, 1968
The simultaneous incubation of 3H-dehydroepiandrosterone sulfate and 14C-dehydroepiandrosterone by soluble and microsomal extracts of rabbit ovaries was investigated.
Merle Mason, Mason, Merle, Payne, Anita H., Anita H. Payne   +3 more
core   +1 more source

Dehydroepiandrosterone replacement in women with adrenal insufficiency [PDF]

, 1999
BACKGROUND: The physiologic role of dehydroepiandrosterone in humans is still unclear. Adrenal insufficiency leads to a deficiency of dehydroepiandrosterone; we therefore, investigated the effects of dehydroepiandrosterone replacement, in patients with ...
Ernst, M, Bidlingmaier, Martin, Ines Koehler, Ernst, Michael, Bruno Allolio, Michael Ernst, Heinrich Maria Schulte, Koehler, Ines, Schulte, Heinrich Maria, Schulte, H M, Arlt, W, Doris Huebler, Oettel, Michael, Huebler, D, Allolio, B, Jan Christoph van Vlijmen, Martin Reincke, Koehler, I, Callies, Frank, Reincke, M, van Vlijmen, J C, Oettel, M, Martin Bidlingmaier, Allolio, Bruno, Michael Oettel, Callies, F, Arlt, Wiebke, Bidlingmaier, M, Wiebke Arlt, Hübler, Doris, van Vlijmen, Jan Christoph, Frank Callies, Reincke, Martin   +32 more
core   +1 more source

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency

Pharmaceuticals, 2018
The CYP17A1 gene regulates sex steroid biosynthesis in humans through 17α-hydroxylase/17,20 lyase activities and is a target of anti-prostate cancer drug abiraterone.
Mónica Fernández-Cancio, Núria Camats, Christa E. Flück, Adam Zalewski, Bernhard Dick, Brigitte M. Frey, Raquel Monné, Núria Torán, Laura Audí, Amit V. Pandey   +9 more
doaj   +1 more source