Results 51 to 60 of about 33,998 (196)

Dehydroepiandrosterone replacement therapy [PDF]

European Journal of Endocrinology, 2001
Dehydroepiandrosterone (DHEA) and its sulphated derivative DHEAS are the most abundant circulating steroids, and are derived from the zona reticularis of the adrenal cortex. The foetal adrenals synthesise signi®cant quantities of DHEA, but production of this steroid falls postnatally.
E M, Gurnell, V K, Chatterjee
openaire   +2 more sources

Annual Research Review: Sex differences in conduct disorder – revisiting existing evidence and exploring future directions

Journal of Child Psychology and Psychiatry, EarlyView.
Conduct disorder (CD) is a common psychiatric disorder in youth, characterized by severe and recurrent aggressive and antisocial behaviors and associated with substantial healthcare and societal costs. Rates of CD increase during adolescence in both sexes, with the male‐to‐female ratio narrowing to approximately 1:1.
Anka Bernhard, Christine M. Freitag, Kerstin Konrad, Lucres Jansen, Andreas G. Chiocchetti, Christina Stadler, Stephane A. De Brito, Graeme Fairchild, Gregor Kohls   +8 more
wiley   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Inhibition of Osteoblast Function by Brucella abortus is Reversed by Dehydroepiandrosterone and Involves ERK1/2 and Estrogen Receptor

Frontiers in Immunology, 2018
Brucella abortus induces an inflammatory response that stimulates the endocrine system resulting in the secretion of cortisol and dehydroepiandrosterone (DHEA).
María Virginia Gentilini, Ayelén Ivana Pesce Viglietti, Paula Constanza Arriola Benitez, Andrea Elena Iglesias Molli, Gloria Edith Cerrone, Guillermo Hernán Giambartolomei, María Victoria Delpino   +6 more
doaj   +1 more source

Commentary: The body embarrassed—A commentary on Černis et al. (2026) and Martinez et al. (2026)

JCPP Advances, EarlyView.
Alexandra Moussa‐Tooks, Natasha Chaku
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

A Study of the Association between Dehydroepiandrosterone and Frailty in Elderly

Journal of the Indian Academy of Geriatrics, 2018
Objective: To determine the association between dehydroepiandrosterone and frailty in the elderly. Methods: In this cross-sectional analytical study, older people aged 65 and above attending the geriatric outpatient and inpatient services were screened ...
P Aravind Babu, S Deepa
doaj  

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Dehydroepiandrosterone and Its Metabolite 5-Androstenediol: New Therapeutic Targets and Possibilities for Clinical Application

Pharmaceuticals
Dehydroepiandrosterone and its sulfate are the most abundant steroids in humans. The metabolism of dehydroepiandrosterone can differ significantly depending on the organ or tissue and the subtype of steroid receptors expressed in it.
Tatiana A. Fedotcheva, Maria E. Uspenskaya, Darya N. Ulchenko, Nikolay L. Shimanovsky   +3 more
doaj   +1 more source

Psychophysical Assessment of Gustatory Function in Burning Mouth Syndrome: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate whether psychophysically assessed gustatory function differs between adults with burning mouth syndrome and age‐ and sex‐matched healthy controls, and to explore related sensory and physiological factors. Methods This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses ...
Abas Jafari, Muhammed Alparslan Gøkhan, Lene Baad‐Hansen   +2 more
wiley   +1 more source