DHEA attenuates PDGF-induced phenotypic proliferation of vascular smooth muscle A7r5 cells through redox regulation. [PDF]
, 2010 It is known that dehydroepiandrosterone (DHEA) inhibits a phenotypic switch in vascular smooth muscle cells (VSMC) induced by platelet-derived growth factor (PDGF)-BB. However, the mechanism behind the effect of DHEA on VSMC is not clear.
Akishita, Masahiro +6 more
core +1 more source
From adrenarche to aging of adrenal zona reticularis: precocious female adrenopause onset
Endocrine Connections, 2020 Objective: Adaptive changes in DHEA and sulfated-DHEA (DHEAS) production from adrenal zona reticularis (ZR) have been observed in normal and pathological conditions.
Emanuelle Nunes-Souza +16 more
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
NEUROBIOLOGICAL EFFECTS OF DHEA IN FEMALES WITH SPECIAL REFERENCE TO SEXUAL FUNCTION: FINDINGS FROM IN-VIVO AND HUMAN STUDIES [PDF]
, 2012 Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body. Nonetheless, their physiological significance, their mechanisms of action and their possible roles in human disease are ...
PLUCHINO, NICOLA
core
Table_1_Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate in Alzheimer's Disease: A Systematic Review and Meta-Analysis.DOC [PDF]
, 2019 Background and Purpose: Previous studies found inconsistent results for the relationship between Alzheimer's disease and the levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate.
Shi Wu Wen (670452) +4 more
core +1 more source
Do Resveratrol and Dehydroepiandrosterone Increase Diminished Ovarian Reserve? [PDF]
, 2020 Objective: In this study, the aim is to observe changes induced by dehydroepiandrosterone (DHEA) and resveratrol (RES) in diminished ovarian follicles that was induced by 4-vinylcyclohexenediepoxide (VCD)
Semra Yigitaslan +9 more
core +1 more source
Journal of Adolescence, EarlyView.ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino +3 more
wiley +1 more source
Dehydroepiandrosterone and dehydroepiandrosterone sulphotransferase activity and expression in human disease [PDF]
, 2009 The adrenal steroid dehydroepiandrosterone (DHEA) and its sulphate ester, DHEAS are the most abundant circulating steroid hormones in humans. Uncongugated DHEA predominately exerts its effects via its downstream conversion to active sex steroids in ...
McNelis, Joanne
core
Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study [PDF]
, 2003 Background: Dehydroepiandrosterone is a steroid hormone used as an 'over-the-counter' drug in the USA. Treatment with dehydroepiandrosterone was effective in randomized controlled trials in patients with systemic lupus erythematosus ...
Schölmerich, J. +5 more
core +1 more source
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids [PDF]
Proceedings of the National Academy of Sciences, 1998 The observation was made that dehydroepiandrosterone (DHEA), as the unconjugated steroid, and its sulfate ester (DHEAS) are present in the brain of adult male rats (1). This finding was unforeseen because the rodent steroidogenic glands, including the adrenals, do not secrete significant amounts of DHEA (2).
E E, Baulieu, P, Robel
openaire +2 more sources