Results 61 to 70 of about 39,056 (236)

Показатели кортизола и дегидроэпиандростеронсульфата как потенциальные биомаркеры эффективности терапии оланзапином у больных с первым психотическим эпизодом

Современная терапия психических расстройств, 2018
Актуальность. Недостаточное количество и противоречивость данных относительно состояния гипоталамо гипофизарно адреналовой оси у больных с первым психотическим эпизодом диктует необходимость исследования уровней кортизола и дегидроэпиандростерон ...
Горобец, Л.Н., Литвинов, А.В., Буланов, В.С.   +2 more
doaj   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

Metabolic Phenotype Predicts Biochemical Response to Inositol Supplementation in Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To evaluate the effect of inositol supplementation on biochemical hyperandrogenism in women with polycystic ovary syndrome (PCOS) and to explore whether metabolic phenotype modifies the endocrine response. Design Systematic review and meta‐analysis of randomized controlled trials conducted in accordance with PRISMA guidelines ...
Daniele Tienforti, Gennaro Puocci, Claudia Venditti, Valentina Gizzi, Carlo Pisanò, Elisa Cocci, Elisabetta Perfetto, Francesco D'Alessandro, Luca Spagnolo, Marco Giorgio Baroni, Arcangelo Barbonetti   +10 more
wiley   +1 more source

LC-MS/MS simultaneous analysis of allopregnanolone; epiallopregnanolone; pregnanolone; dehydroepiandrosterone and dehydroepiandrosterone 3-sulfate in human plasma

, 2017
AIM: Several neuropsychopharmacological properties have been attributed to the 3α-reduced pregnane steroids, allopregnanolone and pregnanolone, as well as to dehydroepiandrosterone sulfate because of their ability to modulate γ-aminobutyric acid (GABAA)
Federica Piras, Orfei, Maria Donata, Luana Lionetto, Lionetto, Luana, Martina Curto, Matilde Capi, Bossã1, Paola, De Andrã©s, Fernando, Gianfranco Spalletta, Donata Sabato, Capi, Matilde, Simmaco, Maurizio, Maurizio Simmaco, Banaj, Nerisa, Piras, Federica, Sabato, Donata, Curto, Martina, Paola Bossù, Nerisa Banaj, Fernando De Andrés, Maria Donata Orfei, Sacchinelli, Eleonora, Spalletta, Gianfranco, Eleonora Sacchinelli   +23 more
core   +1 more source

Melatonin and Dehydroepiandrosterone: An Observation vis-à-vis Infertility

Advances in Human Biology
Introduction: Diminished ovarian reserve (DOR) is interconnected with female childlessness and inadequate backlash observed to ovarian stimulation. The study aimed to compare the effects of melatonin (MT) and dehydroepiandrosterone (DHEA) on ovarian ...
Fatema Haque, Farzana Deeba, Jesmin Banu, Shakeela Ishrat, Arifa Akhter, Susmita Sinha, Rahnuma Ahmad, Mainul Haque   +7 more
doaj   +1 more source

Inhibition of Osteoblast Function by Brucella abortus is Reversed by Dehydroepiandrosterone and Involves ERK1/2 and Estrogen Receptor

Frontiers in Immunology, 2018
Brucella abortus induces an inflammatory response that stimulates the endocrine system resulting in the secretion of cortisol and dehydroepiandrosterone (DHEA).
María Virginia Gentilini, Ayelén Ivana Pesce Viglietti, Paula Constanza Arriola Benitez, Andrea Elena Iglesias Molli, Gloria Edith Cerrone, Guillermo Hernán Giambartolomei, María Victoria Delpino   +6 more
doaj   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, EarlyView.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

Dehydroepiandrosterone sulfate (DHEAS) is neuroprotective when administered either before or after injury in a focal cortical cold lesion model

, 2006
Dehydroepiandrosterone and its sulfate (DHEAS) are sex hormone precursors that exert marked neurotrophic and/or neuroprotective activity in the central nervous system.
Toldi, József, Kis, Zsolt, Rózsa, Éva, Farkas, Tamás, Juhász-Vedres, Gabriella, Párducz, Árpád, Rákos, Gabriella, Wölfling, János, Dobszay B., Gábor   +8 more
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