Results 71 to 80 of about 33,998 (196)

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Changes in Cortisol and Testosterone During Acclimatization and the Relationship to Energetic Outcomes

American Journal of Biological Anthropology, Volume 191, Issue 2, October 2026.
ABSTRACT Objectives When in energetically demanding environments (e.g., high altitude, backcountry expeditions), humans acclimatize to compounded intensive stressors. Acclimatization is possible in part by using the dynamically responsive neuroendocrine system, with changes to hormones like cortisol (CORT) and testosterone (T), which both play ...
Mallika S. Sarma, Cara J. Ocobock, Shannon Rochelle, Sarah Martin, Shalender Bhasin, Clare Super, S. Finn Warrick, Lee T. Gettler   +7 more
wiley   +1 more source

Diagnostic Discordance in Recurrent Pregnancy Loss: Hysteroscopy Resolves Ultrasound–MRI Disagreement in Septate Uterus, but Concurrent Ovulation Induction Precludes Causal Attribution of the Reproductive Outcome

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Congenital uterine anomalies are an important and potentially treatable contributor to recurrent pregnancy loss (RPL). The septate uterus is the commonest Müllerian anomaly linked to first‐trimester loss, and its differentiation from the benign arcuate uterus is essential for management, yet imaging modalities may disagree.
Iftekhar Ahmed Sakib, Ayesa Perveen, Nishad Tasnim   +2 more
wiley   +1 more source

Long-term administration of DHEA prevents fat deposition in rats fed a high-fat diet

Czech Journal of Animal Science, 2016
The effects of dehydroepiandrosterone (DHEA) on lipid metabolism and lipogenic gene mRNA expression in rats subjected to a high-fat diet were determined.
D. Chen, J. Kang, L. Li, H. Ma
doaj   +1 more source

Chronic Central Adrenal Insufficiency in a Patient With Remote Traumatic Brain Injury and an Apparently Adequate Standard‐Dose ACTH Response: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In patients with a remote history of traumatic brain injury, central adrenal insufficiency may remain unrecognized for decades. An apparently adequate response to standard‐dose ACTH stimulation should not preclude further evaluation of the hypothalamic–pituitary–adrenal axis when clinical and biochemical findings continue to suggest adrenal ...
Kazunori Kageyama, Keisuke Sato, Satoshi Yamagata, Mizuki Tasso, Yuki Nakada, Shojiro Sawada   +5 more
wiley   +1 more source

Correlation Analysis of Hypothalamic-Pituitary-Adrenal Axis Hormone Levels in Hair before Stroke Onset and Mood Disorders after Stroke

康复学报
ObjectiveTo explore the expression of hypothalamic-pituitary-adrenal (HPA) axis related hormones such as cortisol (F), cortisone (E) and dehydroepiandrosterone (DHEA) in hair before the onset of stroke and their correlation with post-stroke mood ...
WANG Tiantian, JIA Yuanyuan, QI Deyi, DENG Huihua, MENG Dianhuai   +4 more
doaj  

Effects of DHEA and DHEAS in Neonatal Hypoxic–Ischemic Brain Injury

Antioxidants
Neonatal brain injury remains a significant issue with limited treatment options. This study investigates the potential of the endogenous neurosteroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) as neuroprotective agents, building on ...
Elena Mayer, Ira Winkler, Eva Huber, Martina Urbanek, Ursula Kiechl-Kohlendorfer, Elke Griesmaier, Anna Posod   +6 more
doaj   +1 more source

Hypoxia and dehydroepiandrosterone in old age: a mouse survival study

Respiratory Research, 2006
Background Survival remains an issue in pulmonary hypertension, a chronic disorder that often affects aged human adults. In young adult mice and rats, chronic 50% hypoxia (11% FIO2 or 0.5 atm) induces pulmonary hypertension without threatening life.
Quillard Janine, Baulieu Etienne-Emile, Debonneuil Edouard H   +2 more
doaj   +1 more source

Modulating the Gut–Ovarian Axis: Mechanistic Rationale and the Limits of Current Evidence for Probiotics in Female Reproductive Aging

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Selected orally administered probiotics and functional‐food interventions may alter gut microbial ecology and intestinal barrier function. Microbiota‐derived metabolites, microbial components, and endocrine signals—including short‐chain fatty acids, bile acids, tryptophan metabolites, and lipopolysaccharide—may influence systemic immune, metabolic, and
Meiqi Chen, Qi Su, Mengshuang Sun, He Zhang, Jin Xu, Chenxi Zhang, Yanbo Wang   +6 more
wiley   +1 more source

Neurosteroid Transport in the Brain: Role of ABC and SLC Transporters

Frontiers in Pharmacology, 2018
Neurosteroids, comprising pregnane, androstane, and sulfated steroids can alter neuronal excitability through interaction with ligand-gated ion channels and other receptors and have therefore a therapeutic potential in several brain disorders.
Markus Grube, Paul Hagen, Gabriele Jedlitschky   +2 more
doaj   +1 more source