Results 71 to 80 of about 39,056 (236)

A Study of the Association between Dehydroepiandrosterone and Frailty in Elderly

Journal of the Indian Academy of Geriatrics, 2018
Objective: To determine the association between dehydroepiandrosterone and frailty in the elderly. Methods: In this cross-sectional analytical study, older people aged 65 and above attending the geriatric outpatient and inpatient services were screened ...
P Aravind Babu, S Deepa
doaj  

Down-Regulation of Dehydroepiandrosterone Sulfotransferase Gene in Human Hepatocellular Carcinoma

, 2008
Differential display (DD) PCR cloning of differentially expressed genes in hepatocellular carcinoma (HCC) and adjacent unaffected tissue demonstrated preferential down- regulation of a vital sex steroid precursor ( dehydroepiandrosterone sulfotransferase;
許輝吉, Huang, Lan-Ru; Coughtrie, Michael W.H.; Hsu, Hey-Chi   +1 more
core  

UK Clinical Guideline for Best Practice in the Use of Vaginal Pessaries for Pelvic Organ Prolapse

Neurourology and Urodynamics, EarlyView.
Claire Brown, Angie Rantell, Kate Anders, Lucy Brett, Avril McDowell, Di Tilston, Nicola Wilson, Julia Wilkens, Naz Abbas, Lucy Dwyer, Georgia Smith, Kate Lough   +11 more
wiley   +1 more source

Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu, Jiaying Ni, Qian Dou, Hang Su, Ziyi Zhang, Xiaojing Ma, Qing Dai, Jian Zhou   +7 more
wiley   +1 more source

Design and Synthesis of Novel Dehydroepiandrosterone Analogues as Potent Antiproliferative Agents

Molecules, 2018
The aim of the present study was to determine the cytotoxic effects of a series of novel dehydroepiandrosterone derivatives containing triazole at the C16 position on human cancer cells. The cancer cells used in the present study were A549, Hela, HepG-2,
Xing Huang, Qing-Kun Shen, Hong-Jian Zhang, Jia-Li Li, Yu-Shun Tian, Zhe-Shan Quan   +5 more
doaj   +1 more source

Chronic Depression Alters Mothers’ DHEA and DEHA-to-Cortisol Ratio: Implications for Maternal Behavior and Child Outcomes

Frontiers in Psychiatry, 2020
Maternal depression is a major public health problem that typically occurs in the period surrounding childbirth. The neurobiological mechanisms underlying maternal depression have been the focus of increasing research and studies pointed to the crucial ...
Yael Apter-Levy, Orna Zagoory-Sharon, Ruth Feldman   +2 more
doaj   +1 more source

Short‐Term Combined Treatment With Tirzepatide and Metformin for Overweight/Obese Chinese Women With Polycystic Ovary Syndrome: A Prospective, Open‐Label, Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to assess the effects of low‐dose tirzepatide combined with metformin (COM) versus metformin (MET) monotherapy in overweight/obese women with polycystic ovary syndrome (PCOS). Materials and Methods Sixty overweight/obese women with PCOS were randomised to the MET group (1000 mg twice daily [BID]) or the COM group (MET ...
Zhuoran Yang, Yuxin Xu, Hu Du, Wenya Liu, Haiyan Chen, Dongfang Liu, Lili Zhang, Cong Wang   +7 more
wiley   +1 more source

A Case–Control Study of the Association of Novel Androgens (11-KT and DHT), Classical Androgens (Testosterone and DHEAS), Hormones (LH, FSH, 17-OHP, Insulin, and SHBG), Insulin Resistance (HOMA-IR), and Dyslipidemia in Polycystic Ovarian Syndrome (PCOS)

Advanced Biomedical Research
Background: The measurement of androgens (testosterone and dehydroepiandrosterone sulfate (DHEAS)) remains standard for the evaluation of polycystic ovarian syndrome (PCOS) women.
Nirmal Kumar, Neera Sharma, Smita Roy, Indu Chawla, Lokesh Kumar Sharma   +4 more
doaj   +1 more source

Long-term administration of DHEA prevents fat deposition in rats fed a high-fat diet

Czech Journal of Animal Science, 2016
The effects of dehydroepiandrosterone (DHEA) on lipid metabolism and lipogenic gene mRNA expression in rats subjected to a high-fat diet were determined.
D. Chen, J. Kang, L. Li, H. Ma
doaj   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source