Effect of a delayed-action phenytoin preparation on blood phenytoin concentration [PDF]
In a cross-over study in a group of epileptic patients it was shown that replacement of the evening dose of an ordinary phenytoin preparation with the same phenytoin dose in a delayed-action preparation produced no significant change in the next morning's mean blood phenytoin concentration.
F, Bochner +3 more
openaire +4 more sources
The Pharmacokinetics, Dosage, Preparation Forms, and Efficacy of Orally Administered Melatonin for Non-Organic Sleep Disorders in Autism Spectrum Disorder During Childhood and Adolescence: A Systematic Review [PDF]
Background: To date, it remains unclear which oral doses and preparation forms of melatonin should be recommended for children and adolescents with non-organic sleep disorders and autism spectrum disorder (ASD). We reviewed the current state of knowledge
Ekkehart Paditz +5 more
doaj +2 more sources
Intratumoral sustained release of resiquimod with ablative fractional laser induces efficacy in a cutaneous squamous cell carcinoma mouse model [PDF]
IntroductionThe Toll-like receptor (TLR) 7/8 agonist resiquimod has shown promise for precancerous lesions of cutaneous squamous cell carcinoma (cSCC) but remains unexplored as a treatment for cSCC.
Martin Wiinberg +6 more
doaj +2 more sources
Once-Daily Extended-Release Levetiracetam Improves Medication Compliance in Adolescent Epilepsy Patients [PDF]
Purpose Since pharmacologic agents are the mainstay of epilepsy treatment, drug compliance is one of the most important factors in seizure control. Once-daily levetiracetam (LEV) has been proven to have the same efficacy as that of an immediate-release ...
Seung Yeon Jung +2 more
doaj +1 more source
Retrospective analysis of hospitalization rates in patients with schizophrenia 12 months before and 12 months after the switch on once-monthly long-acting injectable paliperidone palmitate [PDF]
Background/Aim. There is no available published data about the use of long-acting injectable paliperidone palmitate (PP) in schizophrenia patients in the Republic of Serbia.
Totić-Poznanović Sanja +1 more
doaj +1 more source
A case of overdose of fluphenazine decanoate injection
Case description: A 28 years old, married Hindu male from a tea garden community, working as daily wage earner was diagnosed as a case of schizophrenia, paranoid type from psychiatry outpatient department (OPD) of Tezpur Medical College and Hospital ...
Barasha Saharia, Soumitra Ghosh
doaj +1 more source
Adherence to depot versus oral antipsychotic medication in schizophrenic patients during the long-term therapy [PDF]
Background/Aim. There is a high rate of schizophrenic patients who do not adhere to their prescribed therapy, despite the implementation of antipsychotic long-acting injections and the introduction of atypical antipsychotics. The aim of this study was
Stanković Žana, Ille Tatjana
doaj +1 more source
The objective of this study was to evaluate a pH-dependent system of ileocolonic release of active ingredients using the polymer Eudragit® S100. A spouted bed was used in the coating process of soft capsules containing palm oil and of hard capsules ...
Luciana Arantes Soares, Eduardo Crema
doaj +1 more source
A comparative analysis of the influence of different types of Carbopol® on the release rate of lithium-carbonate from matrix tablets [PDF]
Background/Aim. Hydrophilic matrix tablets represent the most commonly used oral dosage form. Carbomers used in the concentration of 10%-30% for preparation of matrix tablets, may significantly affect the profile of drug release due to the formation ...
Toskić-Radojčić Marija +4 more
doaj +1 more source
Aim We conducted a 1‐year retrospective mirror‐image study to investigate the effect of aripiprazole once monthly (AOM) on rehospitalization for bipolar disorder.
Junichi Goto +6 more
doaj +1 more source

