Results 31 to 40 of about 56,045 (301)

Study on Neuromuscular Blockade Action of Verapamil in Albino Rats [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Background: Calcium Channel Blockers (CCBs) are now widely employed in the treatment of cardiovascular diseases and peri-operative hypertension. It has been reported that calcium channel blockers inhibit neuromuscular transmission.
JAYASHREE NAGARAL   +6 more
doaj   +1 more source

Diabetes mellitus attenuates the repolarization reserve in mammalian heart

open access: yes, 2007
Objective: In diabetes mellitus several cardiac electrophysiological parameters are known to be affected. In rodent experimental diabetes models changes in these parameters were reported, but no such data are available in other mammalian species ...
Lengyel, Csaba Attila   +12 more
core   +1 more source

Comparison between immediate and delayed post space preparations: a systematic review and meta-analysis

open access: yes, 2021
Objectives: This systematic review and meta-analysis compared the effects of immediate and delayed post space preparation on apical sealing. Materials and method: Two independent authors conducted a systematic search (PubMed/Medline, Cochrane Library,
Francine Benetti   +8 more
core   +1 more source

Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways. [PDF]

open access: yesPLoS ONE, 2010
Proving the efficacy and corresponding mode of action of herbal supplements is a difficult challenge for evidence-based herbal therapy. A major hurdle is the complexity of herbal preparations, many of which combine multiple herbs, particularly when the ...
Young-Beob Yu   +5 more
doaj   +1 more source

Hollow microneedles as a flexible dosing control solution for transdermal drug delivery

open access: yesMaterials Today Bio
Microneedles, small needle-like structures typically less than 1000 μm in length, are effective tools for transporting substances across biological barriers via minimally invasive pathways.
Jongwon Kim   +3 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Case Report: Atypical neuroleptic malignant syndrome induced by paliperidone palmitate—diagnostic challenges and clinical considerations

open access: yesFrontiers in Psychiatry
Poor treatment adherence is common in schizophrenia and constitutes a major risk factor for relapse and clinical instability. Long-acting injectable (LAI) antipsychotics are frequently prescribed to mitigate this risk; however, their use can be ...
Omar El Oumary   +11 more
doaj   +1 more source

The action of atropine and acetylcholine on the pace maker ganglion cells of limulus heart

open access: yes, 1960
On the median nerve trunk-heart muscle preparation of Limulus the authors studied the effects of atropine and acetylcholine upon the pace maker ganglion cells.
Yamagami, Matuyosi   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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