Results 21 to 30 of about 169,421 (298)

Health care use, drug treatment and comorbidity in patients with schizophrenia or non-affective psychosis in Sweden: a cross-sectional study

open access: yesBMC Psychiatry, 2017
Background This study investigated the prevalence of schizophrenia (ICD-10 F 20) and of other non-affective psychosis (NAP, ICD-10 F 21 - F 29) in Sweden. It further assessed health care use, comorbidity and medication for these patient groups.
Erica M. Brostedt   +3 more
doaj   +1 more source

Forskolin suppresses delayed-rectifier K+ currents and enhances spike frequency-dependent adaptation of sympathetic neurons. [PDF]

open access: yesPLoS ONE, 2015
In signal transduction research natural or synthetic molecules are commonly used to target a great variety of signaling proteins. For instance, forskolin, a diterpene activator of adenylate cyclase, has been widely used in cellular preparations to ...
Luis I Angel-Chavez   +4 more
doaj   +1 more source

Managing constipation in adults with co-morbidities [PDF]

open access: yes, 2016
Constipation can be described in a number of ways but in general it is related to straining, reduced frequency of defecation and/or a sensation of incomplete bowel emptying.
Gardiner, Anji, Hilton, Andrea
core   +2 more sources

Heterogeneity in Kv2 Channel Expression Shapes Action Potential Characteristics and Firing Patterns in CA1 versus CA2 Hippocampal Pyramidal Neurons. [PDF]

open access: yes, 2017
The CA1 region of the hippocampus plays a critical role in spatial and contextual memory, and has well-established circuitry, function and plasticity. In contrast, the properties of the flanking CA2 pyramidal neurons (PNs), important for social memory ...
Brann, David H   +5 more
core   +5 more sources

Antagonistic properties of a probiotic preparation containing bacteria of the genera Bacillus and Enterococcus

open access: yesRegulatory Mechanisms in Biosystems, 2022
Complex probiotic preparations with spore-forming microorganisms of the genus Bacillus and other types of bacteria in their composition have a high biological activity and are of scientific and practical interest.
O. M. Chechet   +7 more
doaj   +1 more source

Diabetes mellitus attenuates the repolarization reserve in mammalian heart [PDF]

open access: yes, 2007
Objective: In diabetes mellitus several cardiac electrophysiological parameters are known to be affected. In rodent experimental diabetes models changes in these parameters were reported, but no such data are available in other mammalian species ...
Biliczki, Péter   +12 more
core   +1 more source

N-terminal arginines modulate plasma-membrane localization of Kv7.1/KCNE1 channel complexes. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND AND OBJECTIVE: The slow delayed rectifier current (I(Ks)) is important for cardiac action potential termination. The underlying channel is composed of Kv7.1 α-subunits and KCNE1 β-subunits.
Zenawit Girmatsion   +5 more
doaj   +1 more source

Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons [PDF]

open access: yes, 2008
Although most spinal cord injuries are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions.
Arko Ghosh   +10 more
core   +2 more sources

The bioavailability of a paediatric sustained-action theophylline capsule

open access: yesSouth African Family Practice, 1985
No abstract available.
R.S. Summers
doaj   +1 more source

The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments. [PDF]

open access: yesPLoS ONE, 2016
In this study the effects of a new, highly selective sodium-calcium exchanger (NCX) inhibitor, ORM-10962 were investigated on cardiac NCX current, Ca2+ transients, cell shortening and in experimental arrhythmias.
Zsófia Kohajda   +25 more
doaj   +1 more source

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