Abstract In radiation oncology, inter‐fractional dosimetry using optically stimulated luminescent detectors (OSLDs) ensures accurate plan delivery and patient safety. RadPro International GmbH's myOLSchip system, featuring a beryllium oxide (BeO) OSL dosimeter, reader, and eraser, was characterized and calibrated with a Varian Truebeam for in‐vivo ...
Heath Davis+3 more
wiley +1 more source
Fermented mistletoe extract as a multimodal antitumoral agent in gliomas [PDF]
In Europe, commercially available extracts from the white-berry mistletoe (Viscum album L.) are widely used as a complementary cancer therapy. Mistletoe lectins have been identified as main active components and exhibit cytotoxic effects as well as ...
Harter, Patrick Nikolaus+4 more
core +2 more sources
Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments
Abstract Prostate Stereotactic Ablative Body Radiotherapy (SABR) is an ultra‐hypofractionated treatment where small setup errors can lead to higher doses to organs at risk (OARs). Although bowel and bladder preparation protocols reduce inter‐fraction variability, inconsistent patient adherence still results in OAR variability.
Conor Sinclair Smith+8 more
wiley +1 more source
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood+5 more
wiley +1 more source
The Oxidative state of LDL is the major determinant of anti/prooxidant effect of coffee on Cu2+ catalysed peroxidation [PDF]
Antioxidants exert contrasting effect on low density lipoprotein (LDL) oxidation catalysed by metals, acting as pro-oxidants under select in vitro conditions.
Carru, Ciriaco+9 more
core
Ovarian function during hormonal contraception assessed by endocrine and sonographic markers: a systematic review [PDF]
This systematic review focuses on the literature evidence for residual ovarian function during treatment with hormonal contraceptives. We reviewed all papers which assessed residual ovarian activity during hormonal contraceptive use, using endocrine ...
Bastianelli, Carlo+5 more
core +1 more source
UDP‐glucose dehydrogenase variants cause dystroglycanopathy
Abstract UDP‐glucose dehydrogenase (UGDH) variants have been associated with hypotonia, developmental delay, and epilepsy. We report the first pathologic evidence of dystroglycanopathy in siblings with UGDH variants. Both presented around 6 months with developmental delay and elevated creatinine kinase.
Anna M. Reelfs+8 more
wiley +1 more source
The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death. [PDF]
Reactive oxygen species (ROS) play a key role in development of heart failure but, at a cellular level, their effects range from cytoprotection to induction of cell death.
Clerk, A+9 more
core +3 more sources
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita+7 more
wiley +1 more source
Use of new, once-daily 5-aminosalicylic acid preparations in the treatment of ulcerative colitis. Is there anything new under the sun? [PDF]
5-aminosalicylate (5-ASA) agents remain the mainstay treatment in ulcerative colitis (UC). A number of oral 5-ASA agents are commercially available, including azobond pro-drugs, as well as delayed- and controlled-release forms of mesalazine.
Lakatos, Péter László
core +2 more sources